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Clareo Health | Colorectal Cancer Clinical Trials in Tennessee | 454 Studies

Clinical Trials Colorectal CancerTennessee

Colorectal Cancer Clinical Trials in Tennessee

Find 454 clinical trials for colorectal cancer near Tennessee. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Tennessee

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

Healthy volunteers too

Showing 1-20 of 454 trials

CompletedLower or Standard Dose Regorafenib in Treating Patients With Refractory Metastatic Colorectal CancerThis randomized phase II trial studies how well lower-dose compared to standard dose regorafenib works in treating patients with colorectal cancer that has spread from the primary…NCT02368886·Phoenix, Arizona and 21 others

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Data from ClinicalTrials.govTerms

Active not recruitingStudy of JANX008 in Subjects With Advanced or Metastatic Solid Tumor MalignanciesThis study is a first-in-human (FIH), Phase 1/1b, open-label, multicenter dose escalation and dose expansion study to assess the safety, tolerability, pharmacokinetics (PK)…NCT05783622·Duarte, California and 17 others

CompletedPhase I Study of Enadenotucirev and PD-1 Inhibitor in Subjects With Metastatic or Advanced Epithelial TumorsThis is a Phase I multicenter, open label, nonrandomized study of enadenotucirev administered in combination with nivolumab in subjects with metastatic or advanced epithelial…NCT02636036·Tucson, Arizona and 5 others

TerminatedStool Sample Collection Protocol for Development of Screening Test for Colorectal Cancer and Other Digestive Tract CancersThe primary objective of this study is to obtain de-identified, clinically characterized, stool and plasma specimens for use in assessing new markers for the detection of…NCT02503631·Newport Beach, California and 21 others

TerminatedSequential and Concurrent FOLFOXIRI/Bevacizumab Regimens Versus FOLFOX/Bevacizumab in First-Line Metastatic Colorectal CancerThis randomized, open-label, multicenter study will evaluate the efficacy and safety of folinic acid (leucovorin), 5-fluorouracil (5-FU), oxaliplatin, and irinotecan (FOLFOXIRI) /…NCT01765582·Mobile, Alabama and 44 others

CompletedPrograms To Support You During ChemotherapyThis randomized pilot trial studies how well two supportive programs work for improving fatigue and depressive symptoms in patients with GI undergoing chemotherapy.NCT02489422·Winston-Salem, North Carolina and 1 other

CompletedPhase 1b/2 Study of AMG 655 With mFOLFOX6 and Bevacizumab for First-Line Metastatic Colorectal CancerThis phase 1/2, multi-center, randomized, double-blind, placebo-controlled trial is designed to evaluate the efficacy and safety of AMG 655 when combined with mFOLFOX6 and…NCT00625651·Hot Springs, Arkansas and 60 others

SuspendedA Study of Gene Edited Autologous Neoantigen Targeted TCR T Cells With or Without Anti-PD-1 in Patients With Solid TumorsThis is a first in human, single arm, open label, Phase 1a/1b study to determine the safety, feasibility, and efficacy of a single dose of NeoTCR-P1 T cells in participants with…NCT03970382·Duarte, California and 8 others

UnknownA Study of Navicixizumab Monotherapy or in Combination in Patients With Select Advanced Solid TumorsThis is a study of navicixizumab monotherapy or in combination with paclitaxel or irinotecan in patients with advanced cancer.NCT05453825·Hot Springs, Arkansas and 7 others

TerminatedStudy of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid TumorsThis study is an open-label, international, multi-center, Phase 2 study in adult patients with recurrent, locally-advanced or metastatic solid tumors, which harbor the NRG1 gene…NCT04383210·Birmingham, Alabama and 41 others

Active not recruitingA Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X MutationsTo evaluate the efficacy of naporafenib administered with trametinib in patients with rat sarcoma viral oncogene (RAS) Q61X solid tumors * To evaluate the safety and tolerability…NCT05907304·San Francisco, California and 28 others

CompletedOxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With SurgeryPURPOSE: This randomized phase III trial is studying giving oxaliplatin, leucovorin calcium, and fluorouracil together to compare how well they work when given together with or…NCT01150045·Mobile, Alabama and 841 others

CompletedEncorafenib, Binimetinib and Cetuximab in Subjects With Previously Untreated BRAF-mutant ColoRectal CancerThe purpose of this study is to evaluate the efficacy and safety of the combination of study drugs encorafenib, binimetinib and cetuximab in patients who have BRAF V600 mutant…NCT03693170·New York, New York and 44 others

TerminatedInformed Choice - CompassThe primary objective of this study is to evaluate the impact of a theoretically grounded video that includes information about CRC screening modality choices on CRC screening…NCT05246839·Phoenix, Arizona and 38 others

TerminatedTovorafenib (DAY101) Monotherapy for Patients With Melanoma and Other Solid TumorsThis is a Phase 2, multi-center, open-label to evaluate the efficacy and safety of tovorafenib (DAY101) in participants ≥12 years of age with recurrent or progressive melanoma or…NCT04985604·Los Angeles, California and 19 others

CompletedA Study of PDR001 in Combination With CJM112, EGF816, Ilaris® (Canakinumab) or Mekinist® (Trametinib)The purpose of this study was to combine the PDR001 checkpoint inhibitor with each of four agents with immunomodulatory activity to identify the doses and schedule for combination…NCT02900664·Baltimore, Maryland and 22 others

TerminatedA Study to Learn About PF-07921585 Alone or With Other Anti-cancer Medicines in People With CancerThe purpose of this study is to learn about the safety and effects of the study medicine (called PF-07921585) in people with cancer that has advanced or spread to other parts of…NCT06580938·Fayetteville, Arkansas and 8 others

RecruitingEfficacy of Perioperative Opioid Sparing Techniques on Time to Initiation of ChemotherapyThe primary purpose of this study is to determine if intrathecal morphine (ITM) administration is superior to quadratus lumborum block or surgeon administered transversus…NCT07153614·Knoxville, Tennessee

CompletedGrowth Factor Levels in the Blood of Patients Undergoing Radiation Therapy for Epithelial CancerRATIONALE: Measuring levels of transforming growth factor-beta (TGF-beta) in the blood of patients with epithelial cancers (head and neck, lung, breast, colorectal, and prostate)…NCT00897793·Nashville, Tennessee and 2 others

Active not recruitingA Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid TumorsThis is a first-in-human study to evaluate the safety, tolerability, pharmacokinetics (PK), and anti-tumor activity of enzelkitug when administered as a single agent and in…NCT05581004·San Francisco, California and 31 others

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