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Clareo Health | Colorectal Cancer Clinical Trials in Pittsburgh | 201 Studies

Clinical Trials Colorectal CancerPittsburgh

Colorectal Cancer Clinical Trials in Pittsburgh

Find 201 clinical trials for colorectal cancer near Pittsburgh, Pennsylvania. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Pittsburgh

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

Who can join

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Showing 21-40 of 201 trials

RecruitingPhase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal CancerA Randomized, Active-Controlled, Double-blind, Multicenter, Phase 3 Clinical Study of Ivonescimab in Combination with mFOLFOX6 (Oxaliplatin, Leucovorin and 5-Fluorouracil) versus…NCT07228832·Mobile, Alabama and 212 others

Colorectal Cancer Trials in Other Cities

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Data from ClinicalTrials.govTerms

Active not recruitingA Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)This is a first-in-human study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022.NCT02817633·Goodyear, Arizona and 88 others

TerminatedPh 1-2 Study ADI-PEG 20 Plus FOLFOX in Subjects With Advanced GI Malignancies Focusing on Hepatocellular CarcinomaPhase 1: Assessment of safety and tolerability of ADI-PEG 20 in combination with folinic acid (leucovorin), fluorouracil and oxaliplatin (FOLFOX) in advanced GI malignancies.NCT02102022·San Francisco, California and 34 others

TerminatedSurgery With or Without Thalidomide in Treating Patients With Recurrent or Metastatic Colorectal CancerRATIONALE: Thalidomide may stop the growth of colorectal cancer by stopping blood flow to the tumor. Giving thalidomide after surgery may kill any remaining tumor cells.NCT00019747·Goshen, Indiana and 5 others

CompletedSurgery With or Without Chemotherapy and Radiation Therapy in TreatingPatients With Stage I Rectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00023751·Anniston, Alabama and 179 others

RecruitingA Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received ChemotherapyThe purpose of this study is to compare how long the participants are disease-free (progression-free survival) and and the length of time until a participant dies (overall…NCT06750094·Chandler, Arizona and 250 others

RecruitingAnastomotic Safety and Surveillance Using Real-time Enhanced Sensing Using xBarPurpose: To evaluate the effect of xBar system utilization on clinical outcomes during recovery following colorectal surgery.NCT07337590·Louisville, Kentucky and 5 others

Active not recruitingUse of ctDNA for Monitoring of Stage III Colorectal CancerThis observational study will evaluate circulating tumor DNA (ctDNA) as a prognostic marker and as a monitor of disease recurrence in stage III colorectal cancer (CRC).NCT02842203·Pittsburgh, Pennsylvania

CompletedStudy of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Previously Treated Metastatic Colorectal CancerThe purpose of this study is to compare treatment with oxaliplatin/5-FU/leucovorin plus vatalanib versus oxaliplatin/5-FU/leucovorin plus placebo in patients with colorectal…NCT00056446·Huntsville, Alabama and 250 others

CompletedA Study to Evaluate Immunotherapy Combinations in Participants With Gastrointestinal MalignanciesThis is a Phase 1/1b, open-label, dose-escalation, and dose-expansion study to evaluate the safety, tolerability, pharmacokinetic (PK), pharmacodynamic (PD), and clinical activity…NCT03720678·Tucson, Arizona and 23 others

CompletedIrinotecan With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00012389·Huntsville, Alabama and 153 others

CompletedCetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal CancerPURPOSE: This randomized phase III trial is studying cetuximab and/or bevacizumab when given together with combination chemotherapy to compare how well they work in treating…NCT00265850·Mobile, Alabama and 682 others

CompletedStudy of Bevacizumab + mFOLFOX6 Versus Bevacizumab + FOLFIRI With Biomarker Stratification in Participants With Previously Untreated Metastatic Colorectal Cancer (mCRC)This will be a randomized, open-label, multicenter, Phase II study with primary objectives to assess whether expression of select chemotherapy markers is associated with…NCT01374425·Birmingham, Alabama and 78 others

TerminatedGenetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE TrialThis trial screens patients with colon or rectal cancer that has spread to other places in the body (metastatic) or cannot be removed by surgery (unresectable) for genetic…NCT03765736·Scottsdale, Arizona and 17 others

TerminatedA Phase 1 Study of MRTX0902 in Solid Tumors With Mutations in the KRAS MAPK PathwayThis is a Phase 1, open-label, multicenter, study evaluating the safety, tolerability, PK, PD, and anti-tumor activity of MRTX0902 alone and in combination with MRTX849…NCT05578092·New Haven, Connecticut and 17 others

Active not recruitingDuloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal CancerThis phase II/III trial studies the best dose of duloxetine and how well it works in preventing pain, tingling, and numbness (peripheral neuropathy) caused by treatment with…NCT04137107·Birmingham, Alabama and 792 others

RecruitingLead-212 PSV359 Therapy for Patients With Solid TumorsPhase I/IIa image-guided, alpha-particle therapy study of \[203Pb\]Pb-PSV359 and \[212Pb\]Pb-PSV359 in patients with solid tumors that are known to be Fibroblast Activation…NCT06710756·Miami, Florida and 10 others

Active not recruitingStudy of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C MutationThis is a phase Ib/II open label study.NCT04699188·Atlanta, Georgia and 37 others

WithdrawnSafety and Efficacy Study of Neratinib and Cetuximab to Treat Patients With Quadruple Wild-Type Metastatic Colorectal CancerThe FC-7 study is designed as an open label, single arm, Phase I/II dose-escalation study evaluating the combination of neratinib and cetuximab in patients with metastatic…NCT01960023·Gainesville, Florida and 11 others

TerminatedCelecoxib in Preventing Polyps in Patients Who Have Undergone Surgery for Stage I Colon CancerRATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development of cancer.NCT00087256·Pittsburgh, Pennsylvania

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