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Clareo Health | Colorectal Cancer Clinical Trials in Philadelphia | 279 Studies

Clinical Trials Colorectal CancerPhiladelphia

Colorectal Cancer Clinical Trials in Philadelphia

Find 279 clinical trials for colorectal cancer near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Philadelphia

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

Who can join

Healthy volunteers too

Showing 61-80 of 279 trials

CompletedA Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid TumorsThis research study is done to test how well different types of cancer respond to the drug called larotrectinib.NCT02576431·Palo Alto, California and 97 others

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Data from ClinicalTrials.govTerms

CompletedRAV12 in Treating Patients With Metastatic or Recurrent AdenocarcinomaRATIONALE: Monoclonal antibodies, such as RAV12, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.NCT00101972·Santa Monica, California and 4 others

CompletedA Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal CancerThis is a Phase 1 study currently evaluating PO administered ompenaclid in combination with FOLFIRI and bevacizumab in patients with advanced (i.e., locally advanced and…NCT03597581·Prescott Valley, Arizona and 16 others

CompletedReducing Colorectal Cancer Death Through Mailed Outreach ScreeningThe main study aim is to develop, implement and disseminate a pilot population-based mailed FIT outreach screening program in the Philadelphia VA Medical Center that does not rely…NCT02584998·Philadelphia, Pennsylvania

RecruitingA Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) MutationThe main purpose of the trial is to assess whether the trial drug, KST-6051, is safe and tolerable when administered orally to adults with advanced or metastatic solid tumors with…NCT07458347·Los Angeles, California and 8 others

CompletedDose-Esc/Exp RMC4630 & Cobi in Relapsed/Refractory Solid Tumors & RMC4630& Osi in EGFR+ Locally Adv/Meta NSCLCThe purpose of this study is to evaluate the safety, tolerability, pharmacokinetic (PK), and pharmacodynamic (PD) proﬁles of RMC-4630 and cobimetinib in adult participants with…NCT03989115·Scottsdale, Arizona and 23 others

CompletedA Study Evaluating the Efficacy and Safety of MEGF0444A Dosed to Progression in Combination With Bevacizumab and mFOLFOX-6 in Participants With Previously Untreated Metastatic Colorectal CancerThis is a Phase II, multicenter, randomized, double-blind, placebo-controlled trial designed to estimate the efficacy of MEGF0444A treatment to disease progression, combined with…NCT01399684·Birmingham, Alabama and 39 others

RecruitingPhase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid TumorsPhase I Study, a master protocol to investigate TCR-Engineered T cells recognizing KRAS mutations in adult subjects with Unresectable, Advanced, and/or Metastatic Solid Tumors.NCT06218914·Duarte, California and 17 others

CompletedStudy of the Safety, Tolerability and Efficacy of KPT-8602 in Participants With Relapsed/Refractory Cancer IndicationsThis is a first-in-human, multi-center, open-label clinical study with separate dose escalation (Phase 1) and expansion (Phase 2) stages to assess preliminary safety…NCT02649790·Los Angeles, California and 45 others

CompletedAdherence to Survivorship Care Guidelines in Health Care Providers for Non-Small Cell Lung Cancer and Colorectal Cancer Survivor CareThis clinical trial studies adherence to survivorship care guidelines in health care providers for non-small cell lung cancer or colorectal cancer survivor care.NCT01726296·Philadelphia, Pennsylvania

UnknownVaccine Therapy and Chemotherapy With or Without Tetanus Toxoid Compared With Chemotherapy Alone in Treating Patients With Metastatic Colorectal CancerRATIONALE: Vaccines may make the body build an immune response to kill tumor cells.NCT00027833·Birmingham, Alabama and 12 others

CompletedClinical Validation of An Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, for Colorectal Cancer Screening "BLUE-C"The primary objective of this study is to assess the sensitivity for colorectal cancer (CRC) and specificity of the mt-sDNA 2.0 test.NCT04144738·Birmingham, Alabama and 194 others

CompletedPhase 2 Study of ABT-869 in Combination With mFOLFOX6 Versus Bevacizumab in Combination With mFOLFOX6 to Treat Advanced Colorectal CancerTo determine the effect of ABT-869 plus mFOLFOX6 compared to bevacizumab plus mFOLFOX6 on disease progression in advanced colorectal cancer.NCT00707889·Chapel Hill, North Carolina and 45 others

TerminatedCombination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655)RATIONALE: Drugs used in chemotherapy, such as irinotecan, fluorouracil, and leucovorin, work in different ways to stop the growth of cancer cells, either by killing the cells or…NCT00023868·Tucson, Arizona and 8 others

RecruitingGUCY2C Prime-Boost Vaccination for Advanced Colorectal and Small Bowel AdenocarcinomasThis is an open-label, non-randomized, single-center, dose-escalation Phase 1 trial using a heterologous prime-boost strategy of vaccination with Ad5.F35-hGUCY2C-PADRE and…NCT07417488·Philadelphia, Pennsylvania

UnknownCirculating Tumor Cells in Patients With Metastatic Colorectal CancerThis study enrolled patients with measurable metastatic colorectal cancer.NCT00133913·Philadelphia, Pennsylvania

Active not recruitingA Study of a Patient-Specific Neoantigen Vaccine in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal CancerThe primary objective of the Phase 2 portion of the study is to characterize the clinical activity of maintenance therapy with GRT-C901/GRT-R902 (patient-specific vaccines) in…NCT05141721·Gilbert, Arizona and 42 others

CompletedEffect of Panitumumab on the Pharmacokinetics of IrinotecanThe primary objective of this study is to determine if panitumumab affects the pharmacokinetic (PK) profile of irinotecan.NCT00563316·Billings, Montana and 11 others

UnknownPersonalized Screening Plans to Increase Colorectal Cancer Screening in Healthy ParticipantsRATIONALE: Developing a personalized screening plan may be more effective than usual care in increasing the number of healthy participants who regularly undergo screening for…NCT00617071·Philadelphia, Pennsylvania

RecruitingA Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid TumorsThis study will assess the safety and efficacy of VS-7375 alone and in combination in patients with advanced solid tumors harboring a KRAS G12D-mutation.NCT07020221·Los Angeles, California and 13 others

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Other Conditions in Philadelphia

Breast Cancer Lung Cancer Prostate Cancer Melanoma Leukemia Lymphoma