Personalized Screening Plans to Increase Colorectal Cancer Screening in Healthy Participants

OBJECTIVES: * To compare the impact of tailored intervention vs standard intervention vs usual care on patient utilization of colorectal cancer (CRC) screening. * To compare the impact of these interventions on CRC screening preference. * To compare the impact of these interventions on patient perceptions about CRC screening. OUTLINE: This is a multicenter study. Participants are stratified by practice and study wave and blocking. Participants are randomized to 1 of 3 arms. * Arm I (usual care): Participants receive usual care in accordance with their normal patterns of interaction with study practices. * Arm II (standard intervention \[SI\]): A generic screening invitation letter, a colorectal cancer (CRC) screening informational booklet, stool blood testing (SBT) cards, and instructions for arranging a colonoscopy screening appointment are mailed to participants on day 15. On day 45, a reminder letter is mailed to participants who have not completed SBT or undergone a screening colonoscopy. * Arm III (tailored navigation intervention \[TNI\]): A test-specific screening invitation letter, a CRC screening informational booklet, and additional test-specific materials (i.e., instructions for arranging a colonoscopy screening appointment or SBT cards) are mailed to participants on day 15. On day 30, a patient navigator contacts participants by telephone who have not completed SBT or undergone a screening colonoscopy. The patient navigator re-assesses screening test-specific decision stage; addresses CRC screening barriers; develops a personalized CRC screening plan to move the participant towards screening use (i.e., explains the steps in completing the SBT or scheduling a colonoscopy appointment); and facilitates screening plan implementation. On day 45, a reminder letter is mailed to participants who were contacted by the navigator. Participants in all arms complete a survey at baseline and then at 6 months. Medical records for each participant are reviewed at 6 months.