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Clareo Health | Colorectal Cancer Clinical Trials in Philadelphia | 279 Studies

Clinical Trials Colorectal CancerPhiladelphia

Colorectal Cancer Clinical Trials in Philadelphia

Find 279 clinical trials for colorectal cancer near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 241-260 of 279 trials

CompletedDose-Esc/Exp RMC4630 & Cobi in Relapsed/Refractory Solid Tumors & RMC4630& Osi in EGFR+ Locally Adv/Meta NSCLCThe purpose of this study is to evaluate the safety, tolerability, pharmacokinetic (PK), and pharmacodynamic (PD) proﬁles of RMC-4630 and cobimetinib in adult participants with…NCT03989115·Scottsdale, Arizona and 23 others TerminatedTACE Plus Axitinib and Hydroxychlorquine for Liver-Dominant Metastatic Colorectal Cancer (CRC)Liver metastases are a leading cause of death among patients with metastatic colorectal cancer. Duration of disease control is short following 2nd-line or later systemic therapy.NCT04873895·Philadelphia, Pennsylvania

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Data from ClinicalTrials.govTerms

CompletedRObotic Versus LAparoscopic Resection for Rectal CancerThe purpose of this study is to compare two different surgical procedures for the treatment of Rectal Cancer: Laparoscopic Surgery and Robotic Assisted Laparoscopic Surgery.NCT01736072·Concord, California and 7 others

RecruitingCollection of Samples USOPTIVAL StudyA prospective multi-center observational study.NCT04792684·Chula Vista, California and 15 others

CompletedStudy of Lenvatinib (MK-7902/E7080) in Combination With Pembrolizumab (MK-3475) Versus Standard of Care in Participants With Metastatic Colorectal Cancer (MK-7902-017/E7080-G000-325/LEAP-017)The purpose of this study is to assess the safety and efficacy of lenvatinib (MK-7902/E7080) in combination with pembrolizumab (MK-3475) in participants with metastatic colorectal…NCT04776148·Monterey, California and 94 others

CompletedAn Exploratory Pharmacogenomic Study of Monotherapy Erbitux in Subjects With Metastic Colorectal CancerThe purpose of this study is to predict response to Erbitux as a single agent in patients with metastatic colon cancerNCT00207155·Duarte, California and 13 others

RecruitingCT-95 in Advanced Cancers Associated With Mesothelin ExpressionThis is a Phase 1a/1b, first-in-human (FIH), open-label, multi-center dose escalation and expansion study of the safety, pharmacokinetics (PK), pharmacodynamics, and antitumor…NCT06756035·Denver, Colorado and 8 others

CompletedComparative Effectiveness of Split-Dose Colonoscopy Bowel Preparation RegimensFrom the patients' perspective, the most formidable part of the colonoscopy experience is the process of bowel cleansing.NCT03298945·Philadelphia, Pennsylvania

CompletedPhase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid TumorsThis is a first-in-human Phase 1a/1b, multicenter, open-label, dose-escalation, dose and schedule optimization, and expansion study of TPST-1495 as a single agent and in…NCT04344795·Aurora, Colorado and 10 others

CompletedGenetic and Environmental Risk Assessment for Colorectal Cancer in Healthy ParticipantsRATIONALE: Evaluating the knowledge and attitudes of healthy participants toward a new diet and gene test for colorectal cancer risk may help doctors improve acceptance of…NCT00087360·Bethesda, Maryland and 3 others

CompletedKorean CRC Screening Study PT13599Korean Americans report the lowest and declined rates of colorectal cancer (CRC) screening, compared to general population in the United States.NCT04478110·Philadelphia, Pennsylvania

RecruitingAMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid TumorsThe purpose of this first-in-human study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary efficacy of AMG 410 when…NCT07094113·Duarte, California and 38 others

CompletedA Study of a Personalized Cancer Vaccine Targeting Shared NeoantigensThe purpose of this study is to evaluate the dose, safety, immunogenicity and early clinical activity of GRT-C903 and GRT-R904, a neoantigen-based therapeutic cancer vaccine, in…NCT03953235·Phoenix, Arizona and 11 others

CompletedA Study of XmAb®20717 in Subjects With Selected Advanced Solid TumorsThis is a Phase 1, multiple dose, ascending dose escalation study to define a MTD/RD and regimen of XmAb20717, to describe safety and tolerability, to assess PK and…NCT03517488·Los Angeles, California and 16 others

RecruitingGUCY2C Prime-Boost Vaccination for Advanced Colorectal and Small Bowel AdenocarcinomasThis is an open-label, non-randomized, single-center, dose-escalation Phase 1 trial using a heterologous prime-boost strategy of vaccination with Ad5.F35-hGUCY2C-PADRE and…NCT07417488·Philadelphia, Pennsylvania

RecruitingStudy of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid TumorsThe purpose of this platform study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of novel RAS(ON) inhibitors combined with…NCT06445062·Chandler, Arizona and 31 others

CompletedCirculating Tumor Material in Colorectal Cancer and MelanomaObservational study to allow the collection of blood and medical information to evaluate the role of circulating tumor material in patients with colorectal cancer and melanomaNCT02907086·Philadelphia, Pennsylvania

CompletedS1613, Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by SurgeryThis randomized phase II trial studies how well trastuzumab and pertuzumab work compared to cetuximab and irinotecan hydrochloride in treating patients with HER2/neu amplified…NCT03365882·Anchorage, Alaska and 797 others

TerminatedColorectal Cancer Treated With Adjuvant Regorafenib Versus Placebo After Curative Treatment of Liver Metastases in a Randomized, Double-blind, Placebo-Controlled Phase-III STudyTo evaluate and compare the efficacy and safety of regorafenib versus placebo in subjects with colorectal cancer (CRC) after curative resection of liver metastasis and completion…NCT01939223·Laguna Hills, California and 120 others

WithdrawnEffect of Probiotics Supplementation on the Side Effects of Radiation Therapy Among Colorectal Cancer PatientsColorectal cancer (CRC) is one of the most common types of cancer worldwide in general and in Jordan in specific.NCT03742596·Amman

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Other Conditions in Philadelphia

Breast Cancer Lung Cancer Prostate Cancer Melanoma Leukemia Lymphoma