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Computerized Tomographic Colonography: Performance Evaluation in a Multicenter Setting
RATIONALE: New diagnostic procedures such as computed tomographic colonography may provide a less invasive method of identifying patients who have colorectal neoplasia. PURPOSE: Diagnostic study to compare the effectiveness of computerized tomographic colonography with that of standard diagnostic procedures in detecting colorectal neoplasia.
OBJECTIVES: I. Compare retrospectively the accuracy of computerized tomographic colonography (CTC) vs pathology and colonoscopy in the detection of clinically important colorectal neoplasia, defined as at least one proven lesion with a diameter measuring at least 1 cm. II. Compare the physician image display preferences and interpretation time across three viewing platforms for CTC images. OUTLINE: This is a retrospective, multicenter study. Radiologists evaluate each patient's optimal diagnostic computerized tomographic colonography (CTC) data. Patients' CTC findings are evaluated by a radiologist at a central facility using an imaging display software platform from General Electric, Vital Images, or the Mayo Clinic. CTC findings are compared with conventional colonoscopy findings and pathologic analysis. A comparison is made between physician image display preferences and interpretation time across three viewing platforms for CTC images. PROJECTED ACCRUAL: A total of 90 patients will be accrued for this study.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
University of Alabama Comprehensive Cancer Center
Birmingham, Alabama, United States
Jonsson Comprehensive Cancer Center, UCLA
Los Angeles, California, United States
Veterans Affairs Medical Center - San Francisco
San Francisco, California, United States
Emory University School of Medicine
Atlanta, Georgia, United States
Boston Medical Center
Boston, Massachusetts, United States
Mayo Clinic Cancer Center
Rochester, Minnesota, United States
Mallinckrodt Institute of Radiology
St Louis, Missouri, United States
NYU School of Medicine's Kaplan Comprehensive Cancer Center
New York, New York, United States
Duke Comprehensive Cancer Center
Durham, North Carolina, United States
Comprehensive Cancer Center of Wake Forest University Baptist Medical Center
Winston-Salem, North Carolina, United States
Start Date
July 1, 2000
Primary Completion Date
October 1, 2000
Completion Date
January 1, 2003
Last Updated
February 4, 2013
computed tomography
PROCEDURE
diagnostic colonoscopy
PROCEDURE
Lead Sponsor
American College of Radiology Imaging Network
Collaborators
NCT06696768
NCT04704661
Data Source & Attribution
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