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Clareo Health | Colorectal Cancer Clinical Trials in Pennsylvania | 498 Studies

Clinical Trials Colorectal CancerPennsylvania

Colorectal Cancer Clinical Trials in Pennsylvania

Find 498 clinical trials for colorectal cancer near Pennsylvania. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 361-380 of 498 trials

RecruitingPost-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal ResectionsThe purpose of this study is to evaluate the safety and performance of the Signia™ power handle, Signia™ circular adapter, and Signia™ Tri-Staple™ 2.0 circular reloads (hereafter…NCT07351071·New Haven, Connecticut and 9 others Active not recruitingPhase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation (KRYSTAL-10)Study CA239-0006 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab versus chemotherapy in the…NCT04793958·Alabaster, Alabama and 418 others

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Data from ClinicalTrials.govTerms

CompletedOxaliplatin and Bevacizumab (Avastin™) With Either Fluorouracil and Leucovorin or Capecitabine in Treating Patients With Advanced Colorectal CancerRATIONALE: Drugs used in chemotherapy, such as oxaliplatin, fluorouracil, leucovorin, and capecitabine, work in different ways to stop tumor cells from dividing so they stop…NCT00062426·Birmingham, Alabama and 51 others

CompletedImproving Fecal Occult Blood Test Completion Rates Among VeteransThis is a 4-arm cluster randomized controlled trial to evaluate whether patient financial incentives directly integrated into primary care can improve fecal occult blood test…NCT01516489·Philadelphia, Pennsylvania

UnknownComparison of Three Chemotherapy Regimens in Treating Patients With Metastatic Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00008281·Huntsville, Alabama and 133 others

CompletedFOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal CancerIn this Phase I/II clinical trial, the investigators seek to pilot the addition of hydroxychloroquine (HCQ) to the standard front-line therapy of colorectal cancer…NCT01206530·Philadelphia, Pennsylvania

CompletedA Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid TumorsThis is a Phase 1, multiple dose, ascending-dose escalation study and expansion study designed to define a maximum tolerated dose and/or recommended dose of XmAb22841 monotherapy…NCT03849469·Encinitas, California and 27 others

UnknownLongitudinal Performance of Epi proColonThis study will evaluate longitudinal performance of Epi proColon with respect to test positivity, longitudinal adherence to Epi proColon screening, adherence to follow-up…NCT03218423·San Diego, California and 5 others

CompletedA Volume, Motion, and Anatomically Adaptive Approach to Photon and Proton Beam RadiotherapyThis pilot study will determine changes over time in tumor volume/motion \& patient anatomy, as well as dose distributions to normal organs.NCT02130427·Philadelphia, Pennsylvania

CompletedBRAF/MEK/EGFR Inhibitor Combination Study in Colorectal Cancer (CRC)This was a four part, phase I/II study aimed to evaluate the safety, tolerability and efficacy of combination of an anti-EGFR antibody panitumumab (P) either with a BRAF inhibitor…NCT01750918·Scottsdale, Arizona and 19 others

CompletedPembrolizumab Combined With Itacitinib (INCB039110) and/or Pembrolizumab Combined With INCB050465 in Advanced Solid TumorsThis is an open-label, multicenter, Phase 1b platform study in subjects with advanced or metastatic solid tumors (Part 1a) and subjects with selected solid tumors (Part 1b and…NCT02646748·San Francisco, California and 16 others

CompletedS9415 Chemotherapy in Patients With Stage II or III Colon Cancer That Has Been Surgically RemovedRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00002593·Scottsdale, Arizona and 59 others

Active not recruitingA Study of XL092 as Single-Agent and Combination Therapy in Subjects With Solid TumorsThis is a Phase 1, open-label, dose-escalation and expansion study, evaluating the safety, tolerability, pharmacokinetics (PK), preliminary antitumor activity, and effect on…NCT03845166·Duarte, California and 85 others

TerminatedIrinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer That Progressed During First-Line TherapyThis randomized phase III trial is studying giving irinotecan and cetuximab together with bevacizumab to see how well it works compared with giving irinotecan and cetuximab alone…NCT00499369·Fort Smith, Arkansas and 381 others

RecruitingSpevatamig (PT886) as Monotherapy or in Combination With Chemo and/or Targeted Therapy and/or ICI, for the Treatment of Patients With Advanced Gastrointestinal Cancers, Including Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)This is a first-in-human, Phase 1/2, open-label, dose escalation and dose expansion and combination study designed to evaluate the safety, tolerability, pharmacokinetics…NCT05482893·Duarte, California and 10 others

UnknownA Study of EZN-2208 Administered With or Without Cetuximab in Patients With Metastatic Colorectal CarcinomaThis is a Phase 2, multicenter, multiple-arm, open-label study to evaluate the efficacy, safety, and tolerability of EZN-2208.NCT00931840·Tucson, Arizona and 59 others

CompletedPhotodynamic Therapy System for Patients With Refractory/Unresponsive Solid TumorsThis multi-center photodynamic therapy study plans to treat patients with large tumors in any superficial location, sarcoma, tumors of oral/oro-pharyngeal cavity, tumors with…NCT00028405·Tucson, Arizona and 5 others

RecruitingCollecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer DetectionThis study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection.NCT05334069·Anchorage, Alaska and 746 others

CompletedReal-Time Monitoring of Chemotherapy Side-Effects in Patients With Gastrointestinal Cancers, RT-CAMSS StudyThis trial tests new methods and materials for the real-time chemotherapy-associated side effects monitoring support system (RT-CAMSS) in patients with gastrointestinal cancers…NCT04449679·Philadelphia, Pennsylvania

TerminatedStudy of Bevacizumab Combined With Capecitabine and Either Oxaliplatin or Irinotecan as First Course of Treatment for Patients With Colorectal Cancer That Has Spread Beyond the ColonBevacizumab is an angiogenesis inhibitor which means it works to stop blood vessel formation in tumors. Without new blood vessels, the growth of a tumor is slowed.NCT00314353·Pittsburgh, Pennsylvania

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Other Conditions in Pennsylvania

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