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Clareo Health | Colorectal Cancer Clinical Trials in Pennsylvania | 498 Studies

Clinical Trials Colorectal CancerPennsylvania

Colorectal Cancer Clinical Trials in Pennsylvania

Find 498 clinical trials for colorectal cancer near Pennsylvania. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 341-360 of 498 trials

RecruitingA Phase 2 Study of Zanidatamab in Patients With HER2-expressing TumorsThe purpose of this study is to evaluate the efficacy and safety of zanidatamab for the treatment of participants with previously treated solid tumors that have Human Epidermal…NCT06695845·Prescott, Arizona and 27 others CompletedLeucovorin and Fluorouracil With or Without SU5416 in Treating Patients With Metastatic Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00004252·Montgomery, Alabama and 25 others

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Data from ClinicalTrials.govTerms

WithdrawnCBX-12 for the Treatment of Metastatic Chemotherapy-Refractory Microsatellite Stable Colorectal CancerThis phase II trial studies how well CBX-12 works in treating patients with microsatellite stable colorectal cancer that has spread to other parts of the body (metastatic) and is…NCT06730100·Irvine, California and 14 others

TerminatedStudy of Labetuzumab Govitecan in Participants With Metastatic Colorectal CancerThe goal of this clinical study is to determine the dosing and safety of labetuzumab govitecan (formerly known as IMMU-130; hMN-14-SN38, antibody-drug conjugate) in participants…NCT01605318·Santa Monica, California and 6 others

CompletedA Phase 1 Study Investigating the Combination of RAD001, Cetuximab and Irinotecan as Second-line Therapy After FOLFOX (or XELOX) Plus Bevacizumab in Patients With Metastatic Colorectal CancerThis study will assess the safety of RAD001 when given together with cetuximab and irinotecanNCT00478634·Fayetteville, Arkansas and 15 others

CompletedBlood and Stool Sample Collection in Subjects Participating in Colorectal Cancer Screening: Act BoldThe primary objective of this study is to collect de-identified, clinically-characterized stool and whole blood specimens for use in developing and evaluating the performance of…NCT03821948·Tempe, Arizona and 39 others

CompletedOctreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal CancerRATIONALE: Octreotide may be effective in preventing or controlling diarrhea in patients who are undergoing chemoradiotherapy for anal or rectal cancer.NCT00075868·Mobile, Alabama and 111 others

TerminatedA Study of BDTX-189, an Orally Available Allosteric ErbB Inhibitor, in Patients With Advanced Solid Tumors.This was a clinical study with an orally administered drug, BDTX-189 in participants with advanced solid tumors that had select mutations or alterations in human epidermal growth…NCT04209465·Scottsdale, Arizona and 37 others

Terminated89Zr-girentuximab for PET Imaging of CAIX Positive Solid TumorsA prospective, open-label, phase 2 study to explore CAIX expression through 89Zirconium-labelled girentuximab deferoxamine (89Zr-girentuximab) PET/CT imaging in patients with…NCT05563272·Los Angeles, California and 9 others

CompletedA Study of Xeloda (Capecitabine) Compared With 5-Fluorouracil in Combination With Low-Dose Leucovorin in Patients Who Have Undergone Surgery for Colon CancerThis 2 arm study will compare the safety and efficacy of oral Xeloda, or 5-fluorouracil in combination with leucovorin, in patients who have undergone surgery for colon cancer.NCT00009737·Birmingham, Alabama and 132 others

RecruitingA Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received ChemotherapyThe purpose of this study is to compare how long the participants are disease-free (progression-free survival) and and the length of time until a participant dies (overall…NCT06750094·Chandler, Arizona and 250 others

CompletedTrial Of Irinotecan In Combination With Three Methods Of Administration Of Fluoropyrimidine.This study compares in the first study period combination of Irinotecan with three different methods of administration by Fluoropyrimidine. (ie. infusion, bolus and oral).NCT00101686·Birmgingham, Alabama and 174 others

RecruitingSafety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the IleostomyThe purpose of this study is to evaluate the Colorectal Balloon Tube (hereinafter referred to as COLO-BT™) device, a single use, temporary intraluminal bypass device, intended to…NCT05826743·Buffalo, New York and 2 others

CompletedA Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced MalignanciesThis is a study to determine the maximum tolerated dose (MTD) for CDX-1140 (CD40 antibody), either alone or in combination with CDX-301 (FLT3L), pembrolizumab, or chemotherapy and…NCT03329950·Scottsdale, Arizona and 10 others

CompletedPhysician-Initiated Stop-Smoking Program for Patients Receiving Treatment for Early-Stage CancerRATIONALE: Physician-initiated smoking cessation strategies may be effective in getting early-stage cancer patients to quit smoking.NCT00002520·Philadelphia, Pennsylvania

TerminatedA Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and BevacizumabA study to evaluate the efficacy and tolerability of ABT-165 plus FOLFIRI compared to bevacizumab plus FOLFIRI in participants with previously treated metastatic adenocarcinoma of…NCT03368859·Chandler, Arizona and 64 others

Not yet recruitingDecision Counseling and Follow-up for Shield+ PatientsProspective, observational, minimal-risk study evaluating decision-making, decisional conflict, intention to undergo complete diagnostic evaluation (CDE), and colonoscopy…NCT07620535·Philadelphia, Pennsylvania

CompletedSorafenib and Bevacizumab in Treating Patients With Metastatic Colorectal CancerThis phase II trial is studying how well giving sorafenib together with bevacizumab works in treating patients with metastatic colorectal cancer.NCT00826540·Scottsdale, Arizona and 210 others

RecruitingA Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal CancerA Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients with Refractory Advanced/Metastatic Microsatellite Stable Colorectal CancerNCT06992258·New Haven, Connecticut and 12 others

CompletedMGD019 DART® Protein in Unresectable/Metastatic CancerThe purpose of this study is to evaluate the safety and tolerability, pharmacokinetics (PK) pharmacodynamics and preliminary antitumor activity of lorigerlimab.NCT03761017·Chicago, Illinois and 38 others

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Other Conditions in Pennsylvania

Breast Cancer Lung Cancer Prostate Cancer Melanoma Leukemia Lymphoma