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Clareo Health | Colorectal Cancer Clinical Trials in Detroit | 167 Studies

Clinical Trials Colorectal CancerDetroit

Colorectal Cancer Clinical Trials in Detroit

Find 167 clinical trials for colorectal cancer near Detroit, Michigan. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Detroit

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

Healthy volunteers too

Showing 41-60 of 167 trials

TerminatedA Study to Evaluate U3-1402 in Subjects With Advanced or Metastatic Colorectal CancerThis study is designed to primarily evaluate the safety and efficacy of U3-1402 in participants with advanced or metastatic colorectal cancer (CRC) who have received at least 2…NCT04479436·Fayetteville, Arkansas and 45 others

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Data from ClinicalTrials.govTerms

TerminatedPF-07284892 in Participants With Advanced Solid TumorsThe purpose of this first-in-patient, open label study is to determine the maximum tolerated dose and/or recommended dose for further study of PF-07284892 as a single agent and in…NCT04800822·Phoenix, Arizona and 10 others

Active not recruitingColonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM)Colorectal cancer (CRC) is currently the second most common cause of cancer death in the United States, and one of the most preventable cancers.NCT01239082·Phoenix, Arizona and 45 others

CompletedNintedanib (BIBF 1120) vs Placebo in Refractory Metastatic Colorectal Cancer (LUME-Colon 1)The objective of this Phase III study is to evaluate the efficacy of nintedanib in patients with metastatic colorectal cancer (mCRC) after failure of previous treatment with…NCT02149108·Los Angeles, California and 128 others

CompletedHealth Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon CancerRATIONALE: Participating in a physical activity program designed to increase free time physical activity and receiving written health education materials may influence the chance…NCT00819208·Detroit, Michigan and 46 others

CompletedBryostatin 1 in Treating Patients With Metastatic Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00003220·Detroit, Michigan and 1 other

No longer availableRegorafenib in Subjects With Metastatic Colorectal Cancer (CRC) Who Have Progressed After Standard TherapyThis is a phase III B, prospective, interventional, open-label, single-arm, multicenter study to provide regorafenib to subjects diagnosed with metastatic colorectal cancer who…NCT01538680·Duarte, California and 206 others

RecruitingA Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid TumorsThe main purpose of this study is to evaluate the safety and preliminary efficacy of CHS-114 in combination with toripalimab and/or other standard of care (SOC) compound(s) in…NCT06657144·Tucson, Arizona and 29 others

RecruitingStudy of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid TumorsThis study is to evaluate the safety, tolerability, and PK profiles of Elironrasib and Daraxonrasib as monotherapies and combination therapy in patients with KRAS G12C-mutated…NCT06128551·Duarte, California and 55 others

Active not recruitingTesting the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT StudyThis phase III trial studies how well combination chemotherapy, bevacizumab, and/or atezolizumab work in treating patients with deficient deoxyribonucleic acid (DNA) mismatch…NCT02997228·Kingman, Arizona and 444 others

Active not recruitingM6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by SurgeryThis phase I trial studies the side effects and best dose of M6620 and irinotecan hydrochloride in treating patients with solid tumors that have spread to other places in the body…NCT02595931·Los Angeles, California and 22 others

Active not recruitingDuloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal CancerThis phase II/III trial studies the best dose of duloxetine and how well it works in preventing pain, tingling, and numbness (peripheral neuropathy) caused by treatment with…NCT04137107·Birmingham, Alabama and 792 others

UnknownA First-in-Human Study of SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid TumorsThis proposed Phase I clinical trial of SON-DP is an FIH, open-label, Phase Ia/Ib dose escalation and expansion study to evaluate the safety, tolerability, PK, and PD of SON-DP in…NCT05989724·Gilbert, Arizona and 4 others

TerminatedA Study of NM21-1480 in Adult Patients With Advanced Solid TumorsThis is a first-in-human, open-label, multi-center, Phase 1/2, dose-escalation study with expansion cohorts to evaluate NM21-1480 for safety and immunogenicity, to determine the…NCT04442126·Fort Collins, Colorado and 25 others

RecruitingA Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid TumorsThis is a Phase 1/2 open-label, multi-center, multi-national study with an initial dose escalation part to determine the recommended Phase II dose (RP2D) of MCLA-158 single agent…NCT03526835·La Jolla, California and 53 others

RecruitingCollecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer DetectionThis study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection.NCT05334069·Anchorage, Alaska and 750 others

CompletedAvelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor)This is a Phase 1, open-label, dose-escalation trial of avelumab \[antibody targeting programmed death ligand 1 (anti PD-L1)\] with consecutive parallel group expansion in…NCT01772004·Goodyear, Arizona and 73 others

CompletedCetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal CancerPURPOSE: This randomized phase III trial is studying cetuximab and/or bevacizumab when given together with combination chemotherapy to compare how well they work in treating…NCT00265850·Mobile, Alabama and 682 others

UnknownPROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing SurgeryThe standard treatment for locally advanced rectal cancer involves chemotherapy and radiation, known as 5FUCMT, (the chemotherapy drugs 5-fluorouracil/capecitabine and radiation…NCT01515787·Birmingham, Alabama and 1072 others

CompletedAzacitidine and Entinostat in Treating Patients With Metastatic Colorectal CancerThis phase II trial is studying how well giving azacitidine together with entinostat works in treating patients with metastatic colorectal cancer.NCT01105377·Scottsdale, Arizona and 13 others

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