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Clareo Health | Colorectal Cancer Clinical Trials in Detroit | 167 Studies

Clinical Trials Colorectal CancerDetroit

Colorectal Cancer Clinical Trials in Detroit

Find 167 clinical trials for colorectal cancer near Detroit, Michigan. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Detroit

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 21-40 of 167 trials

CompletedStudy of Irinotecan and Cetuximab Versus Irinotecan as Second-Line Treatment in Patients With Metastatic, EGFR-Positive Colorectal CancerThe purpose of this study is to determine whether overall survival is prolonged in subjects with metastatic, epidermal growth factor receptor (EGFR)-positive colorectal cancer…NCT00063141·Tucson, Arizona and 187 others

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Data from ClinicalTrials.govTerms

RecruitingA Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal CancerThe purpose of this study is to compare how long the participants are disease-free (progression-free survival) when treated with amivantamab and chemotherapy with 5-fluorouracil…NCT06662786·Gilbert, Arizona and 238 others

CompletedPhase I Study of Enadenotucirev and PD-1 Inhibitor in Subjects With Metastatic or Advanced Epithelial TumorsThis is a Phase I multicenter, open label, nonrandomized study of enadenotucirev administered in combination with nivolumab in subjects with metastatic or advanced epithelial…NCT02636036·Tucson, Arizona and 5 others

CompletedDetection of Advanced Colorectal Neoplasia by Stool DNA in Inflammatory Bowel DiseaseThis study aims to determine the performance of the Exact IBD-ACRN surveillance test to detect colorectal cancer (CRC) and colorectal neoplasia in patients with inflammatory bowel…NCT01819766·Phoenix, Arizona and 25 others

TerminatedA Study of ASP1951 in Subjects With Advanced Solid TumorsThe primary purpose of this study is to evaluate the tolerability and safety profile of ASP1951 when administered as a single agent and in combination with pembrolizumab in…NCT03799003·Tucson, Arizona and 31 others

RecruitingKO-2806 Monotherapy and Combination Therapies in Advanced Solid TumorsThis first-in-human (FIH) dose-escalation and dose-validation/expansion study will assess KO-2806, a farnesyltransferase inhibitor (FTI), as a monotherapy and in combination, in…NCT06026410·Phoenix, Arizona and 37 others

Active not recruitingA Study of a Patient-Specific Neoantigen Vaccine in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal CancerThe primary objective of the Phase 2 portion of the study is to characterize the clinical activity of maintenance therapy with GRT-C901/GRT-R902 (patient-specific vaccines) in…NCT05141721·Gilbert, Arizona and 42 others

RecruitingA Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received ChemotherapyThe purpose of this study is to compare how long the participants are disease-free (progression-free survival) and and the length of time until a participant dies (overall…NCT06750094·Chandler, Arizona and 250 others

TerminatedA Phase 1a/1b FIH Study of PY159 and in Combination With Pembrolizumab in Subjects With Advanced Solid TumorsThis is an open-label, multicenter, First-In-Human (FIH), Phase 1a/1b study of PY159 in subjects with locally advanced (unresectable) and/or metastatic solid tumors that are…NCT04682431·Los Angeles, California and 16 others

CompletedRomidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver DysfunctionThis phase I trial studies the side effects and best dose of romidepsin in treating patients with lymphoma, chronic lymphocytic leukemia, or solid tumors with liver dysfunction.NCT01638533·Duarte, California and 11 others

CompletedA Study With Neoadjuvant mFOLFOX7 Plus Cetuximab to Determine the Surgical Conversion Rate for Unresectable Colorectal Cancer With Metastases Confined to the LiverFC-6 is a Phase II, multi-center clinical trial for patients with unresectable, wild-type K-RAS, colorectal cancer with metastases confined to the liver.NCT00803647·Loma Linda, California and 22 others

TerminatedStudy of Imprime PGG® in Combination With Cetuximab in Subjects With Recurrent or Progressive KRAS Wild Type Colorectal CancerStudy BT-CL-PGG-CRC1031 is a Phase 3, open-label, randomized, multi-center study.NCT01309126·Florence, Alabama and 52 others

CompletedA Study of LY2880070 in Participants With Advanced or Metastatic CancerThe main purpose of this 3-part study is to evaluate the safety and efficacy of the study drug known as LY2880070 in participants with advanced or metastatic solid tumors.NCT02632448·Boston, Massachusetts and 15 others

Active not recruitingPhase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors that have a…NCT03785249·Birmingham, Alabama and 221 others

TerminatedA Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal CancerThis is a randomized, open-label, dose/schedule optimization study comparing NUC-3373/leucovorin (LV)/irinotecan plus bevacizumab (NUFIRI-bev) to 5-FU/LV/irinotecan plus…NCT05678257·Newark, Delaware and 58 others

CompletedStudy of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 GeneOpen-label, Phase I-II, first-in-human (FIH) study for A166 monotherapy in HER2-expressing or amplified patients who progressed on or did not respond to available standard…NCT03602079·Sarasota, Florida and 9 others

CompletedOxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With SurgeryPURPOSE: This randomized phase III trial is studying giving oxaliplatin, leucovorin calcium, and fluorouracil together to compare how well they work when given together with or…NCT01150045·Mobile, Alabama and 841 others

RecruitingPhase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid TumorsThis first-in-human, open-label, multicenter, multi-arm dose-escalation study is designed to evaluate the safety, PK, and PD of ADU-1805, an anti- SIRPα monoclonal antibody, as…NCT05856981·Detroit, Michigan and 10 others

CompletedSafety and Tolerability of DS-7423 in Subjects With Advanced Solid Malignant TumorsThis will be a Phase 1, open-label study of DS-7423 to assess its safety and tolerability, identify a RP2D, (recommended Phase 2 Dose) and assess its Pharmacokinetics (PK) (what…NCT01364844·Detroit, Michigan and 2 others

RecruitingA Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)This open-label, exploratory study is designed to evaluate the safety and efficacy of targeted therapies or immunotherapy as single agents or combinations, in participants with…NCT04929223·Birmingham, Alabama and 83 others

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