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Clareo Health | Colorectal Cancer Clinical Trials in Cleveland | 183 Studies

Clinical Trials Colorectal CancerCleveland

Colorectal Cancer Clinical Trials in Cleveland

Find 183 clinical trials for colorectal cancer near Cleveland, Ohio. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Cleveland

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 41-60 of 183 trials

TerminatedRadial Reload Laparoscopic LAR Case SeriesTo evaluate the Radial Reload Stapler during laparoscopic low anterior resection (LAR) or anterior proctosigmoidectomy for rectal cancer by assessing the primary and secondary…NCT01706822·Cleveland, Ohio TerminatedKZR-261 in Subjects With Advanced Solid MalignanciesA first-in-human, open-label, multicenter, Phase 1 study of KZR-261 designed to assess the safety and tolerability, preliminary anti-tumor activity, and pharmacokinetics (PK) of…NCT05047536·Los Angeles, California and 11 others RecruitingA Study to Investigate the Safety and Efficacy of KQB368 as Monotherapy in Participants With Advanced Solid MalignanciesThe goal of this study is to learn if KQB368 works to treat advanced solid malignancies in adults. The study will also learn about the safety of KQB368.NCT07542704·Los Angeles, California and 13 others

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Data from ClinicalTrials.govTerms

RecruitingJAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS AlterationThis study is to evaluate the safety and tolerability of pan-KRAS inhibitor JAB-23E73 Monotherapy and in Combination with Other Agents in adult participants with advanced solid…NCT06973564·Rochester, Minnesota and 3 others

CompletedOhio Colorectal Cancer Prevention InitiativeThe purpose of the Ohio Colorectal Cancer Prevention Initiative (OCCPI) is to reduce morbidity and mortality due to colorectal cancer (CRC) in the state of Ohio.NCT01850654·Akron, Ohio and 48 others

CompletedLaparoscopic-Assisted Resection or Open Resection in Treating Patients With Rectal CancerThis study is being done to compare two types of surgery currently used for rectal cancer.NCT00726622·Scottsdale, Arizona and 36 others

CompletedS1613, Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by SurgeryThis randomized phase II trial studies how well trastuzumab and pertuzumab work compared to cetuximab and irinotecan hydrochloride in treating patients with HER2/neu amplified…NCT03365882·Anchorage, Alaska and 797 others

CompletedOctreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal CancerRATIONALE: Octreotide may be effective in preventing or controlling diarrhea in patients who are undergoing chemoradiotherapy for anal or rectal cancer.NCT00075868·Mobile, Alabama and 111 others

RecruitingPhase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive MalignanciesBDTX-4933-101 is a first-in-human, open-label, Phase 1/2 dose escalation, dose optimization and expansion study designed to evaluate the safety and tolerability of S241656 as…NCT05786924·Gilbert, Arizona and 48 others

RecruitingTesting for Safety and Colorectal Cancer Preventive Effects of ONC201The purpose of this phase I trial is to test the safety and cancer preventive effects of different doses of ONC201 in people with familial adenomatous polyposis (FAP) or a history…NCT05630794·Ann Arbor, Michigan and 4 others

RecruitingTesting the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur TrialThis phase III trial compares the addition of total ablative therapy to the usual systemic therapy versus the usual systemic therapy alone in treating patients with advanced…NCT05673148·Kingman, Arizona and 194 others

RecruitingAssessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology ClinicsThis is a multi-site clinical study enrolling 2000 newly diagnosed patients with breast, colorectal, melanoma, non-Hodgkin lymphoma, or non-small cell lung cancer, who are…NCT06418204·Fairbanks, Alaska and 490 others

RecruitingA Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal CancerThis study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab or panitumumab and cetuximab plus mFOLFOX in patients with metastatic KRAS G12D -…NCT07659795·Scottsdale, Arizona and 29 others

CompletedCombination Chemotherapy in Treating Patients With Advanced Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.NCT00039611·Anchorage, Alaska and 18 others

CompletedStudy of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Previously Treated Metastatic Colorectal CancerThe purpose of this study is to compare treatment with oxaliplatin/5-FU/leucovorin plus vatalanib versus oxaliplatin/5-FU/leucovorin plus placebo in patients with colorectal…NCT00056446·Huntsville, Alabama and 250 others

RecruitingA Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)Researchers are looking for a better way to treat people who have solid tumors with HER2-activating mutations.NCT06760819·Birmingham, Alabama and 53 others

RecruitingStudy of CP-383 in Patients With Advanced or Metastatic Solid TumorsThe goal of this clinical trial is to learn if an investigational drug CP-383 works to treat advanced cancer. It will also learn about the safety of CP-383.NCT07030257·Denver, Colorado and 12 others

Active not recruitingA Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid TumorThe primary objective of this study is to assess the safety and tolerability and to determine the recommended Phase 2 dose (RP2D) of E7386 in combination with other anticancer…NCT04008797·Little Rock, Arkansas and 105 others

CompletedCB-839 + Capecitabine in Solid Tumors and Fluoropyrimidine Resistant PIK3CA Mutant Colorectal CancerThis study has two portions.NCT02861300·Cleveland, Ohio and 1 other

CompletedStudy of Irinotecan and Cetuximab Versus Irinotecan as Second-Line Treatment in Patients With Metastatic, EGFR-Positive Colorectal CancerThe purpose of this study is to determine whether overall survival is prolonged in subjects with metastatic, epidermal growth factor receptor (EGFR)-positive colorectal cancer…NCT00063141·Tucson, Arizona and 187 others

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