Chronic Pain Clinical Trials in Chicago

Showing 1-20 of 49 trials

A Bionic Breast Project Using Neuroprosthesis to Reduce Chronic Pain After Mastectomy

NCT06382272

This trial seeks to establish whether or not touch sensation can be restored to the breast via neural stimulation. Data will also be obtained to inform future feasibility (including safety), efficacy, and acceptability trials.

MastectomyBreastChronic Pain

University of Chicago8 participantsStarted May 2025

Chicago, Illinois, United States

Not Yet RecruitingPhase 22.2 miles

Paracervical Block With Combined Ketorolac and Lidocaine for Osmotic Dilator Placement

NCT07487246

The purpose of this study is to improve pain management for participantswho need osmotic dilators for cervical preparation the day before their second trimester abortion procedure. Osmotic dilators are sticks that are inserted into the cervix. They soak up fluid and expand overnight, gently opening the cervix. We are studying an injection of ketorolac (a liquid anti-inflammatory medication similar to ibuprofen) combined with lidocaine (a liquid numbing medication), which is injected vaginally to the area surrounding the cervix. Ketorolac is approved by the U.S. Food and Drug Administration (FDA) for intravenous (IV) and intramuscular injection and has been studied as a paracervical injection for participants having first trimester abortion procedures in the office. It has not previously been studied for osmotic dilator insertion.

Pain ManagementAbortionSecond Trimester Abortion+1 more

Rush University Medical Center76 participantsStarted May 2026

Chicago, Illinois, United States

A Bionic Breast Project Using Neuroprosthesis to Reduce Chronic Pain After Mastectomy

Paracervical Block With Combined Ketorolac and Lidocaine for Osmotic Dilator Placement

Chronic Pain Trials in Other Cities

The Thrive Study: Improving Multimodal Physical Function in Adults With Heterogenous Chronic Pain

SCS as an Option for Chronic Low Back and/or Leg Pain Instead of Surgery

Cognitive Behavioral Therapy and Real-Time Pain Management Intervention for Sickle Cell Via Mobile Applications

Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure

External Sensing and Neuromodulation to Assess Diabetic Pain Outcomes (XANADO)

Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Control During Cervical Dilator Placement Prior to Dilation and Evacuation

Postpartum Pain Experience and Attitudes About Opioid Prescribing

rTMS for Relieving Chronic OA Pain

Neuromodulation and Yoga for Mild Traumatic Brain Injury and Chronic Pain

Optimization of NIBS for Treatment of Addiction

Efficacy and Safety of Oxmorphone Extended Release in Chronic Non-malignant Pain

SynerFuse Spinal Fusion and Neuromodulation Proof of Concept Study

BioWave High-frequency Neurostimulation Versus TENS for the Treatment of Chronic Low Back Pain

StimRouter Registry Clinical Protocol

A Depression and Opioid Pragmatic Trial in Pharmacogenetics (DCRI Coordinating Center)

Electrically Evoked Compound Action Potentials Human Observation Medtronic Algorithm Comparison Study

Clinical Study Of a Micro-Implantable Pulse Generator For The Treatment of Peripheral Neuropathic Pain

Development/Testing of SUMMIT: a Tool to Help Patients Manage Pain While Tapering Opioids

Other Conditions in Chicago