Breast Cancer Clinical Trials

Showing 4081-4100 of 5,597 trials

MK2206 in Combination With Anastrozole, Fulvestrant, or Anastrozole and Fulvestrant in Treating Postmenopausal Women With Metastatic Breast Cancer

NCT01344031

This phase I trial studies the side effects and the best dose of MK 2206 (Akt inhibitor MK2206) when given with anastrozole, fulvestrant, or anastrozole and fulvestrant in treating postmenopausal women with breast cancer that has spread to other parts of the body. Estrogen can cause the growth of breast cancer cells. Hormone therapy using anastrozole or fulvestrant may fight breast cancer by lowering the amount of estrogen the body makes. Akt inhibitor MK2206 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving Akt inhibitor MK2206 together with anastrozole, fulvestrant, or anastrozole and fulvestrant may kill more tumor cells.

Estrogen Receptor PositiveInvasive Breast CarcinomaRecurrent Breast Carcinoma+1 more

National Cancer Institute (NCI)31 participantsStarted Apr 2011

St Louis, Missouri, United States

UNKNOWN

Radiomics of Mp-MRI Assessing NAC Outcome in Breast Cancer

NCT03592004

This is a single-arm, multicentre study that aims to assess whether Radiomics combining multiparametric MRI and clinical data could be a good predictor of the responses to neoadjuvant chemotherapy in Breast Cancer.

Breast CancerRadiomicsNeoadjuvant Chemotherapy+1 more

Chinese Academy of Sciences500 participantsStarted Jul 2018

Beijing, China

COMPLETEDNA

Analgesic Effect to Postoperative Pain After Mastectomy: Ultrasound-guided Serratus Anterior Plane Block

NCT02483923

Ultrasound guided serratus anterior plane block may decrease acute postoperative pain and consumption of opioid after mastectomy.

Breast Cancer

Yonsei University40 participantsStarted Jun 2015

Seoul, South Korea

MK2206 in Combination With Anastrozole, Fulvestrant, or Anastrozole and Fulvestrant in Treating Postmenopausal Women With Metastatic Breast Cancer

Radiomics of Mp-MRI Assessing NAC Outcome in Breast Cancer

Analgesic Effect to Postoperative Pain After Mastectomy: Ultrasound-guided Serratus Anterior Plane Block

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