Age

20–any

Sex

FEMALE

Healthy volunteers

Not accepted

1. Patients with histologically proven breast cancer
2. Age, at least 20 years
3. ER/PR/HER2 (negative/negative/negative
* ER/PR negative: nuclear reaction \< 1%, Allred score 0 or 2
* HER2 negative: HER2; IHC (immunohistochemistry) 0,1+ or FISH/SISH (-) in case of IHC 2+
4. Clinically stage II or III with histologically proven lymph-node involvement (T \>1.5 cm or lymph node \[LN\] \>1.5 cm)
5. Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1
6. No prior hormonal treatment, chemotherapy or radiotherapy is allowed.
7. Adequate hematologic, liver and kidney function
8. Written informed consent

Additional 4 Cycles of Cisplatin (CDDP4) in Patients With Triple Negative Breast Cancer for Neoadjuvant Chemotherapy