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Clinical Trials Breast CancerOhio

Breast Cancer Clinical Trials in Ohio

Find 986 clinical trials for breast cancer near Ohio. Connect with research centers in your area.

All Breast Cancer trials nationwide All trials in Ohio

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 141-160 of 986 trials

CompletedEffect of Zoledronic Acid as Anti-Cancer Treatment in Metastatic Breast Cancer PatientsThis study will evaluate zoledronic acid's anti-cancer effects and Circulating Tumor Cell (CTCs) measurements in patients with HER2-negative metastatic breast cancer without bone…NCT01129336·Fayetteville, Arkansas and 32 others

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Data from ClinicalTrials.govTerms

Active not recruitingStudy BT8009-100 in Subjects With Nectin-4 Expressing Advanced MalignanciesThis study is a Phase I/II, multicenter, first-in-human, open-label dose-escalation study of BT8009 given as a single agent and in combination with pembrolizumab in participants…NCT04561362·Denver, Colorado and 23 others

Active not recruitingExemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or MetastaticThis randomized phase III trial studies exemestane and entinostat to see how well they work compared to exemestane alone in treating patients with hormone receptor-positive breast…NCT02115282·Birmingham, Alabama and 652 others

CompletedT-DM1 and Palbociclib for Metastatic HER2 Breast CancerThis is a single arm, phase II study to evaluate if the combination of T-DM1 with palbociclib improves progression-free survival in patients with metastatic HER2 positive breast…NCT03530696·Tucson, Arizona and 15 others

CompletedCombination Chemotherapy in Treating Women With Breast CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.NCT00003519·Birmingham, Alabama and 133 others

CompletedType I-Polarized Autologous Dendritic Cell Vaccine With Tumor Blood Vessel Antigen-Derived Peptides in Metastatic Breast Cancer PatientsThis pilot clinical trial studies the safety of a dendritic cell vaccine when given with gemcitabine hydrochloride in treating patients with breast cancer that has spread beyond…NCT02479230·Cleveland, Ohio and 1 other

RecruitingA Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor TypesThe primary objectives of the study are: (1) in the dose-escalation part: to evaluate safety and tolerability and to determine the recommended Phase 2 dose (RP2D) of farletuzumab…NCT04300556·Tucson, Arizona and 57 others

CompletedStudy Evaluating Neratinib Versus Lapatinib Plus Capecitabine For ErbB2 Positive Advanced Breast CancerThis is a study of an experimental drug (neratinib) versus a combination of drugs (lapatinib and capecitabine) in women who have erbB-2 (HER-2) positive metastatic or locally…NCT00777101·Tucson, Arizona and 151 others

Active not recruitingProspective Pilot Study of Robot-assisted Nipple Sparing Mastectomy (RNSM)This is a pilot study to determine safety, efficacy, and potential risks of robot assisted nipple sparing mastectomy (RNSM), by utilizing the daVinci surgical system.NCT04537312·Columbus, Ohio

RecruitingStudy of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.This is a multicenter randomized, open label study to evaluate overall survival with the Bria-IMT regimen in combination with Checkpoint Inhibitor \[Retifanlimab\], versus…NCT06072612·Phoenix, Arizona and 78 others

Active not recruitingOmega 3 Fatty Acids and ERPR(-)HER2(+/-) Breast Cancer PreventionThe study aims to determine biological changes associated with a low vs high dose of omega 3 fatty acids, docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), over 12 months…NCT02295059·Duarte, California and 1 other

CompletedCombination of Oral WX-671 Plus Capecitabine vs. Capecitabine Monotherapy in First-line Her2-negative Metastatic Breast CancerThis randomized, double-blind, placebo controlled phase II trial is studying how well capecitabine works when given in combination with WX-671 or when given alone in treating…NCT00615940·New York, New York and 19 others

Active not recruitingA Video Intervention to Improve Patient Understanding of Tumor Genomic Testing in Patients With Metastatic CancerThis clinical trial tests whether a video intervention improves patient understanding of tumor genomic testing in patients with cancer that has spread to other parts of the body…NCT05215769·Columbus, Ohio and 3 others

CompletedAssessment of Candidate Protein Expression in Breast Cancer SpecimensRATIONALE: Studying the genes expressed in samples of tumor tissue from patients with cancer may help doctors identify biomarkers related to cancer.NCT00918892·Cleveland, Ohio

Active not recruitingPhase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)The study is intended to show superiority of AZD9833 in combination with CDK4/6 inhibitor (palbociclib, abemaciclib or ribociclib) versus aromatase inhibitors (anastrozole or…NCT04964934·Phoenix, Arizona and 263 others

CompletedStudy of Glembatumumab Vedotin (CDX-011) in Patients With Metastatic, gpNMB Over-Expressing, Triple Negative Breast CancerThe main purpose of this study is to see whether CDX-011 (glembatumumab vedotin, an antibody-drug conjugate) is effective in treating patients who have advanced Triple-Negative…NCT01997333·Birmingham, Alabama and 139 others

RecruitingA Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast CancerThe purpose of this study is to assess the safety of GDC-4198 alone and in combination with giredestrant and also the efficacy of GDC-4198 + giredestrant versus abemaciclib +…NCT07100106·Huntsville, Alabama and 76 others

TerminatedA Phase 1 Study of 68Ga-R11228 and 177Lu-R11228 in Breast CancerA phase 1 study of 68Ga-R11228 and 177Lu-R11228 in breast cancer.NCT07121244·Indianapolis, Indiana and 6 others

RecruitingA Study of MT-4561 in Patients With Various Advanced Solid TumorsThis is a First In Human (FIH), multicenter, open-label, Phase I/II study to evaluate safety, tolerability, Pharmacokinetics (PK), pharmacodynamics, and efficacy of MT-4561 in…NCT06943521·Los Angeles, California and 5 others

CompletedBlood Sample Collection to Evaluate Biomarkers in Subjects With Untreated Solid TumorsThe primary objective of this study is to obtain de-identified, clinically characterized, whole blood specimens to evaluate biomarkers associated with cancer for diagnostic assay…NCT03662204·Phoenix, Arizona and 118 others

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Other Conditions in Ohio

Lung Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma