Breast Cancer Clinical Trials in Boston

Showing 441-460 of 598 trials

Akt Inhibitor MK2206 in Treating Patients With Advanced Breast Cancer

NCT01277757

This phase II trial studies how well Akt inhibitor MK2206 works in treating patients with breast cancer cancer that has spread to other places in the body and usually cannot be cured or controlled with treatment. Akt inhibitor MK2206 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Recurrent Breast CarcinomaStage IIIB Breast CancerStage IIIC Breast Cancer+1 more

National Cancer Institute (NCI)30 participantsStarted Mar 2011

Boston, Massachusetts, United States • Boston, Massachusetts, United States • New York, New York, United States +2 more locations

COMPLETEDPhase 2< 1 mile

A Study of Ipatasertib (GDC-0068) in Combination With Paclitaxel as Neoadjuvant Treatment for Participants With Early Stage Triple Negative Breast Cancer

NCT02301988

This is a randomized, double-blind, placebo-controlled, multicenter, pre-operative Phase II study designed to estimate the efficacy of ipatasertib combined with paclitaxel chemotherapy versus placebo combined with paclitaxel chemotherapy in women with Stage Ia - IIIa triple-negative breast adenocarcinoma. The anticipated time on study treatment is 12 weeks.

Breast Cancer

Genentech, Inc.151 participantsStarted Feb 2015

Tucson, Arizona, United States • Santa Barbara, California, United States • Lakewood, Colorado, United States +39 more locations

Akt Inhibitor MK2206 in Treating Patients With Advanced Breast Cancer

A Study of Ipatasertib (GDC-0068) in Combination With Paclitaxel as Neoadjuvant Treatment for Participants With Early Stage Triple Negative Breast Cancer

Breast Cancer Trials in Other Cities

Anastrozole or Tamoxifen in Treating Postmenopausal Women With Ductal Carcinoma in Situ Who Are Undergoing Lumpectomy and Radiation Therapy

Study of Letrozole With or Without BYL719 or Buparlisib, for the Neoadjuvant Treatment of Postmenopausal Women

Docetaxel and PTK787 in Metastatic Breast Cancer Patients and Gynecological Cancer Patients

Exercise and Metformin in Colorectal and Breast Cancer Survivors

Proactive Psychiatry Consultation for Patients With Cancer and Severe Mental Illness

Vaccination of Patients With Breast Cancer With Dendritic Cell/Tumor Fusions and IL-12

Chemotherapy With or Without Bevacizumab in Treating Women With Stage I, Stage II, or Stage IIIA Breast Cancer That Can Be Removed By Surgery

NOLAN: Naproxen or Loratadine and Neulasta

Cryoablation of Small Breast Tumors in Early Stage Breast Cancer

An Observational Study in Patients With HER2 Positive Metastatic Breast Cancer (SystHERs Registry)

Prospective Observational Study Evaluating Treatment Decision Impact of Prosigna® in Early Stage Breast Cancer Patients

Study Evaluating Neratinib (HKI-272) In Combination With Vinorelbine In Subjects With Solid Tumors And Metastatic Breast Cancer

Study Evaluating The Combination Of Neratinib And Capecitabine In Solid Tumors And Breast Cancer

RAPID: Randomized Trial of Accelerated Partial Breast Irradiation

A Phase 1/2 Study Of HKI-272 (Neratinib) in Combination With Trastuzumab (Herceptin) In Subjects With Advanced Breast Cancer

A Study of a Combination of Trastuzumab and Capecitabine With or Without Pertuzumab in Patients With HER2-positive Metastatic Breast Cancer (PHEREXA)

Phase 2 Trial of AEZS-108 in Chemotherapy Refractory in Triple Negative Breast Cancer

Surgical Resection With or Without Axillary Lymph Node Dissection in Treating Women With Node-Negative Breast Cancer and Sentinel Lymph Node Micrometastases

Other Conditions in Boston