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Clareo Health | Brain Cancer Clinical Trials in Ohio | 172 Studies

Clinical Trials Brain CancerOhio

Brain Cancer Clinical Trials in Ohio

Find 172 clinical trials for brain cancer near Ohio. Connect with research centers in your area.

All Brain Cancer trials nationwide All trials in Ohio

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 1-20 of 172 trials

Active not recruitingPediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPGIndoximod was developed to inhibit the IDO (indoleamine 2,3-dioxygenase) enzymatic pathway, which is important in the natural regulation of immune responses.NCT04049669·Augusta, Georgia and 4 others CompletedA Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent GlioblastomaThe primary objective of this study is to evaluate the safety, efficacy and clinical activity of Pamiparib in combination with radiation therapy (RT) and/or temozolomide (TMZ) in…NCT03150862·Tucson, Arizona and 21 others

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Data from ClinicalTrials.govTerms

TerminatedCelecoxib in Patients With Newly Diagnosed GBM Who Are Receiving Anticonvulsant Drugs and Undergoing RTRATIONALE: Celecoxib may stop the growth of tumor cells by blocking the enzymes necessary for their growth.NCT00068770·Tampa, Florida and 6 others

CompletedA Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)In this research study, we want to learn about the safety of the study drugs, ribociclib and everolimus, when given together at different doses after radiation therapy.NCT03355794·Washington D.C., District of Columbia and 6 others

CompletedA Study of a Retroviral Replicating Vector Combined With a Prodrug Administered to Patients With Recurrent Malignant GliomaThis is a multicenter, open-label, ascending-dose trial of the safety and tolerability of increasing doses of Toca 511, a Retroviral Replicating Vector (RRV), administered to…NCT01156584·Duarte, California and 9 others

RecruitingSafety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP LossThis is a first in human study of TNG456 alone and in combination with abemaciclib in patients with advanced or metastatic solid tumors known to have an MTAP loss.NCT06810544·Scottsdale, Arizona and 14 others

CompletedSafety & Radiation Distribution Study of Cotara® in Patients With Recurrent Glioblastoma MultiformeRATIONALE: Cotara® is an experimental new treatment that links a radioactive isotope (iodine 131) to a targeted monoclonal antibody.NCT00509301·Phoenix, Arizona and 3 others

CompletedPhenylacetate in Treating Children With Recurrent or Progressive Brain TumorsRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00003241·Los Angeles, California and 5 others

Active not recruitingMaximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)This is a multi-center, sequential cohort, open-label, volume and dose escalation study of the safety, tolerability, and distribution of 186RNL given by convection enhanced…NCT01906385·Manhasset, New York and 3 others

Active not recruitingVorinostat and Temozolomide in Treating Patients With Malignant GliomasThis phase I trial is studying the side effects and best dose of vorinostat when given together with temozolomide in treating patients with malignant gliomas.NCT00268385·Birmingham, Alabama and 16 others

CompletedCombination Adenovirus + Pembrolizumab to Trigger Immune Virus EffectsGlioblastoma (GBM) and gliosarcoma (GS) are the most common and aggressive forms of malignant brain tumor in adults and can be resistant to conventional therapies.NCT02798406·Little Rock, Arkansas and 14 others

CompletedDovitinib in Treating Patients With Recurrent or Progressive GlioblastomaThis phase II trial studies how well dovitinib works in treating patients with recurrent or progressive glioblastoma.NCT01753713·Cleveland, Ohio

CompletedChemotherapy in Treating Patients With Progressive or Recurrent Brain TumorsRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00012038·Birmingham, Alabama and 9 others

CompletedSurgery Followed by Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeRATIONALE: Internal radiation uses radioactive material placed directly into or near a tumor to kill tumor cells.NCT00053183·Birmingham, Alabama and 9 others

CompletedHSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain TumorsThis study is a clinical trial to determine the safety of injecting G207 (a new experimental virus therapy) into a recurrent or progressive brain tumor.NCT02457845·Birmingham, Alabama and 1 other

RecruitingStudy of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutantThe goal of this study is to determine the efficacy of the 1) ribociclib and everolimus to treat pediatric and young adult patients newly diagnosed with a high-grade glioma (HGG)…NCT05843253·Aurora, Colorado and 19 others

CompletedAcupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic ChemotherapyRATIONALE: Acupressure wristbands may prevent or reduce nausea and caused by chemotherapy.NCT01346267·Long Beach, California and 24 others

CompletedBevacizumab and Sorafenib in Treating Patients With Recurrent Glioblastoma MultiformeRATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.NCT00621686·Scottsdale, Arizona and 203 others

CompletedRadiation Therapy and Tamoxifen in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma MultiformeRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as tamoxifen may make the tumor cells more sensitive to radiation therapy.NCT00006388·Birmingham, Alabama and 256 others

CompletedTesting Ramipril to Prevent Memory Loss in People With GlioblastomaThis study is to determine if an oral drug called Ramipril can lower the chance of memory loss in patients with glioblastoma getting chemoradiation.NCT03475186·Anchorage, Alaska and 422 others

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