Brain Cancer Clinical Trials in Minneapolis

Showing 21-40 of 58 trials

Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors

NCT02052648

In this study, investigators will conduct a phase I/II trial in recurrent (temozolomide resistant) glioma patients. The overall goal of this study is to provide a foundation for future studies with indoximod tested in newly diagnosed glioblastoma patients with radiation and temozolomide, or in combination with vaccine therapies.

Glioblastoma MultiformeGliomaGliosarcoma+1 more

NewLink Genetics Corporation160 participantsStarted Mar 2014

Castro Valley, California, United States • Los Angeles, California, United States • Orange, California, United States +14 more locations

COMPLETEDPHASE1< 1 mile

Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

NCT01922076

This phase I trial studies the side effects and the best dose of adavosertib when given together with local radiation therapy in treating children with newly diagnosed diffuse intrinsic pontine gliomas. Adavosertib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radiation therapy uses high energy x-rays, gamma rays, neutrons, protons, or other sources to kill tumor cells and shrink tumors. Giving adavosertib with local radiation therapy may work better than local radiation therapy alone in treating diffuse intrinsic pontine gliomas.

Anaplastic AstrocytomaAnaplastic OligoastrocytomaDiffuse Intrinsic Pontine Glioma+3 more

National Cancer Institute (NCI)46 participantsStarted Sep 2013

Birmingham, Alabama, United States • Los Angeles, California, United States • Orange, California, United States +21 more locations

Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors

Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

Brain Cancer Trials in Other Cities

Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy

Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Temozolomide and Radiation Therapy With or Without Cediranib Maleate in Treating Patients With Newly Diagnosed Glioblastoma

Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors

Expanded Access Protocol Using 131I-MIBG

A Study of FT-2102 in Patients With Advanced Solid Tumors and Gliomas With an IDH1 Mutation

Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies

UNITE Study: Understanding New Interventions With GBM ThErapy

A Study of PX-866 in Patients With Glioblastoma Multiforme at Time of First Relapse or Progression

HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers

A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer

Study of XL184 (Cabozantinib) in Adults With Glioblastoma Multiforme

Steady State Blood Volume Maps Using Ferumoxytol Non-stoichiometric Magnetite MRI in Imaging Patients With Glioblastoma

Glioma Supra Marginal Incision Trial

A Phase 1 Study Evaluating AMG 232 in Advanced Solid Tumors or Multiple Myeloma

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

Other Conditions in Minneapolis