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Clinical Trials Brain CancerMinneapolis

Brain Cancer Clinical Trials in Minneapolis

Find 46 clinical trials for brain cancer near Minneapolis, Minnesota. Connect with research centers in your area.

All Brain Cancer trials nationwide All trials in Minneapolis

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 1-20 of 46 trials

CompletedCombination Adenovirus + Pembrolizumab to Trigger Immune Virus EffectsGlioblastoma (GBM) and gliosarcoma (GS) are the most common and aggressive forms of malignant brain tumor in adults and can be resistant to conventional therapies.NCT02798406·Little Rock, Arkansas and 14 others CompletedBevacizumab and Sorafenib in Treating Patients With Recurrent Glioblastoma MultiformeRATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.NCT00621686·Scottsdale, Arizona and 203 others

Brain Cancer Trials in Other Cities

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Data from ClinicalTrials.govTerms

CompletedTesting Ramipril to Prevent Memory Loss in People With GlioblastomaThis study is to determine if an oral drug called Ramipril can lower the chance of memory loss in patients with glioblastoma getting chemoradiation.NCT03475186·Anchorage, Alaska and 422 others

CompletedTemozolomide Plus Lomustine Followed by Radiation Therapy in Treating Patients With High-Grade Malignant GliomaRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00006024·Birmingham, Alabama and 234 others

RecruitingREMIND Maintenance Radiotherapy for Newly Diagnosed GlioblastomaREMIND is a single-center feasibility study testing maintenance radiotherapy in adult patients with newly diagnosed glioblastoma.NCT07831772·Minneapolis, Minnesota

CompletedA Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial TherapyThis is an event driven, adaptive design, a randomized, active-controlled, multicenter, open-label, parallel groups, Phase 3 study of DSP-7888 Dosing Emulsion plus Bevacizumab…NCT03149003·Birmingham, Alabama and 60 others

RecruitingStudy of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIIIThe purpose of this study is to see if combining silevertinib with temozolomide after surgery and radiotherapy helps treat newly diagnosed glioblastoma (GBM) better than using…NCT07326566·Birmingham, Alabama and 37 others

CompletedSelinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade GliomasThis phase I trial studies the side effects and best dose of selinexor in treating younger patients with solid tumors or central nervous system (CNS) tumors that have come back…NCT02323880·Birmingham, Alabama and 22 others

CompletedDasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or GliosarcomaThis phase II trial studies how well dasatinib works in treating patients with glioblastoma multiforme or gliosarcoma that has come back.NCT00423735·Mobile, Alabama and 187 others

CompletedPhase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed GlioblastomaThis 2-arm, randomized, phase III study will investigate the efficacy and safety of the addition of rindopepimut (an experimental cancer vaccine that may act to promote…NCT01480479·Birmingham, Alabama and 222 others

CompletedClinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade GliomaThis is a 2 strata pilot trial within the Pacific Pediatric Neuro-Oncology Consortium (PNOC).NCT03739372·San Diego, California and 11 others

CompletedBevacizumab and Irinotecan or Temozolomide in Treating Patients With Recurrent or Refractory Glioblastoma Multiforme or GliosarcomaThis randomized phase II trial is studying the side effects and how well giving bevacizumab together with irinotecan or temozolomide works in treating patients with recurrent or…NCT00433381·Mobile, Alabama and 92 others

CompletedBevacizumab With or Without Trebananib in Treating Patients With Recurrent Brain TumorsThis partially randomized phase II trial with a safety run-in component studies the side effects and how well bevacizumab given with or without trebananib works in treating…NCT01609790·Anchorage, Alaska and 243 others

CompletedVorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord TumorsThis phase I trial is studying the side effects and best dose of vorinostat when given together with temozolomide in treating young patients with relapsed or refractory primary…NCT01076530·Chicago, Illinois and 8 others

TerminatedVaccine Therapy With Bevacizumab Versus Bevacizumab Alone in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by SurgeryThis randomized phase II trial studies how well giving vaccine therapy with or without bevacizumab works in treating patients with recurrent glioblastoma multiforme that can be…NCT01814813·Anchorage, Alaska and 416 others

CompletedStudy of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain TumorsIn this study, investigators will conduct a phase I/II trial in recurrent (temozolomide resistant) glioma patients.NCT02052648·Castro Valley, California and 16 others

WithdrawnStudy of Therapy With TransMID™ Compared to Best Standard of Care in Patients With Glioblastoma MultiformeTransMID treatment or best standard of care for patients with advanced glioblastoma multiforme Glioblastoma multiforme (GBM) is a type of brain tumour.NCT00083447·La Jolla, California and 24 others

CompletedBevacizumab With or Without Anti-Endoglin Monoclonal Antibody TRC105 in Treating Patients With Recurrent Glioblastoma MultiformeThis partially randomized phase I/II trial studies the side effects and the best dose of anti-endoglin monoclonal antibody TRC105 when given together with bevacizumab and to see…NCT01648348·Little Rock, Arkansas and 307 others

CompletedStudy of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain TumorsThis is a first-in-children phase 1 trial using indoximod, an inhibitor of the immune "checkpoint" pathway indoleamine 2,3-dioxygenase (IDO), in combination with…NCT02502708·Aurora, Colorado and 4 others

CompletedDasatinib or Placebo, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma MultiformeDasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It may also make tumor cells more sensitive to radiation therapy.NCT00869401·Hartford, Connecticut and 206 others

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