Asthma Clinical Trials in Philadelphia

Showing 141-160 of 406 trials

Prognostic Value of Point of Care Cardiac and Lung Ultrasound in COVID-19

NCT04379544

This is a protocol-driven observational study of lung ultrasound and focused echocardiography images obtained in the Emergency Department (ED) and Intensive Care Unit (ICU) settings as a part of existing standard of care. The objectives of this study are as follows: 1. To characterize various clinical and cardiopulmonary ultrasound findings and describe their relationship with the clinical course of patients with COVID-19 in the ED and ICU. 2. To describe, develop, and validate a prediction tool that can accurately predict the need for invasive mechanical ventilation (IMV) and acute respiratory failure in COVID-19 patients using clinical, laboratory, and ultrasound data.

CoronavirusRespiratory Failure

University of Pennsylvania125 participantsStarted Apr 2020

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of MTPS9579A in Patients With Asthma Requiring Inhaled Corticosteroids and a Second Controller

NCT04092582

This is a Phase IIa, randomized, placebo-controlled, double-blind, multicenter, two-arm study to evaluate the efficacy, safety, and pharmacokinetics of MTPS9579A as an add-on therapy in patients with uncontrolled moderate to severe asthma who are receiving daily ICS therapy and at least one of the following additional controller medications: long-acting beta-agonist (LABA), leukotriene modulator (leukotriene modifier \[LTM\] or leukotriene receptor antagonist \[LTRA\]), long-acting muscarinic antagonist (LAMA), or long-acting theophylline preparation.

Asthma

Genentech, Inc.135 participantsStarted Oct 2019

Bakersfield, California, United States • Walnut Creek, California, United States • Miami, Florida, United States +24 more locations

Prognostic Value of Point of Care Cardiac and Lung Ultrasound in COVID-19

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of MTPS9579A in Patients With Asthma Requiring Inhaled Corticosteroids and a Second Controller

Asthma Trials in Other Cities

Respiratory Monitoring System Safety and Performance Study

A Study to Test if TEV-48574 is Effective in Relieving Asthma

A Study to Test if TEV-53275 is Effective in Relieving Asthma

Evaluation of Performance of the LumiraDx Influenza A/B + RSV Test at POC Testing Sites

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

A 24-Week Treatment Study to Compare Standard of Care Versus the eMDPI DS in Participants 13 Years or Older With Asthma

Mite Asthma Pediatric Immunotherapy Trial

Blood Volume Assessment in COVID-19 and Bacterial Sepsis

Clinical Use Cases Assessment of the Gabi System in Young Children With Underlying Medical Conditions (BRIDGE Study)

Children's Respiratory and Environmental Workgroup

A Study to Evaluate the Efficacy and Safety of CC-90001 in Subjects With Idiopathic Pulmonary Fibrosis

(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC

Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial

Study to Assess Efficacy and Safety of Inhaled Interferon-β Therapy for COVID-19

Double-Blind, Randomized, Placebo-Controlled, Multi-Center Phase 3 Study to Evaluate the Efficacy and Safety of Fostamatinib in COVID-19 Subjects

A Study to Evaluate Safety and Immunogenicity of One or Two Booster Vaccinations With H5N6 Influenza Vaccine in Adults Primed With H5N1 Influenza Vaccine or Unprimed

A 3-week Study Investigating Patient Use and Functionality of Formoterol in a Novel Inhalation Device in Patients With Asthma

PK/PD and Long Term Safety Study of Benralizumab in Children With Severe Eosinophilic Asthma

Other Conditions in Philadelphia