Asthma Clinical Trials

Showing 1-20 of 3,299 trials

Sample Collections From the Airways of Asthmatic Patients

NCT00001888

Fiberoptic bronchoscopy is a procedure which involves passing a pencil-thin tube into the lung in order to collect fluid and cells from the airways. Fiberoptic bronchoscopy can collect cells from the walls of airways by gently brushing them (bronchial brushing). In addition, squirting small amounts of sterile water in to the airway and gently suctioning it back into the bronchoscope (bronchoalveolar lavage) collects cells. In this study, researchers plan to perform these tests on patients with asthma and normal volunteers. This research may help to improve the understanding of the processes involved in airway inflammation and asthma....

Asthma

National Heart, Lung, and Blood Institute (NHLBI)574 participantsStarted Jun 1999

Bethesda, Maryland, United States

RECRUITINGPhase 3

Depemokimab Asthma Imaging and Bronchoscopy Sub-Study

NCT06979323

Asthma is a chronic condition marked by narrowed and swollen airways due to inflammation leading to recurring symptoms that can vary and worsen unpredictably.\\xa0The purpose of this study is to assess how depemokimab, a monoclonal antibody, affects the structure and function of the lungs in asthmatic participants with type 2 inflammation, characterized by an eosinophilic phenotype.

Asthma

GlaxoSmithKline150 participantsStarted Jun 2025

Brooksville, Florida, United States • Plantation, Florida, United States • Kansas City, Kansas, United States +40 more locations

Sample Collections From the Airways of Asthmatic Patients

Depemokimab Asthma Imaging and Bronchoscopy Sub-Study

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