ALS Clinical Trials

Showing 1221-1240 of 1,413 trials

Direct-acting Antivirals and Hepatocellular Carcinoma Recurrence

NCT03197155

Background and Aims: Arrival of direct-acting antiviral (DAA) agents against hepatitis C virus (HCV) with high-sustained virological response (SVR) rates and very few side effects has drastically changed the management of HCV infection. The impact of DAA exposure on hepatocellular carcinoma (HCC) recurrence after a first remission in patients with advanced fibrosis remains to be clarified. Methods: 68 consecutive HCV patients with a first HCC diagnosis and under remission, subsequently treated or not with a DAA combination, were included. Clinical, biological, and virological data were collected at first HCC diagnosis, at remission and during the surveillance period.

Hepatocellular CarcinomaHepatitis CDirect Acting Antivirals

Hospices Civils de Lyon68 participantsStarted Jun 2016

COMPLETEDPhase 1/2

SOD1 Inhibition by Pyrimethamine in Familial Amyotrophic Lateral Sclerosis (ALS)

NCT01083667

The objective of this study will be to evaluate the safety, tolerability and effect on SOD1 levels by pyrimethamine in patients with familial amyotrophic lateral sclerosis.

Familial Amyotrophic Lateral Sclerosis

Weill Medical College of Cornell University32 participantsStarted Nov 2009

New York, New York, United States • Houston, Texas, United States • Ulm, Germany +2 more locations

UNKNOWN

Corpus Callosum Size in Patients With Pineal Cyst

NCT03183427

This study aims to determine size of corpus callosum on midsagittal MR scan in patients with a pineal cyst and to compare it with the control group without a pineal cyst.

Pineal Gland DisorderCorpus Callosum AtrophyCerebral Palsy

Military University Hospital, Prague200 participantsStarted Sep 2017

Direct-acting Antivirals and Hepatocellular Carcinoma Recurrence

SOD1 Inhibition by Pyrimethamine in Familial Amyotrophic Lateral Sclerosis (ALS)

Corpus Callosum Size in Patients With Pineal Cyst

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