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To evaluate the blood pressure lowering effects of thiazide diuretics in patients on peritoneal dialysis
This prospective, single-center treatment-withdrawal crossover study enrolled 10 patients on chronic peritoneal dialysis (PD) and uncontrolled hypertension (SBP \>140 mmHg and/or DBP \>90 mmHg). Following written informed consent, participants entered the treatment arm, receiving oral hydrochlorothiazide once daily on top of their standard of treatment for 90 days. This was followed by a 14-day washout period, after which participants entered a 90-day control period.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Prince of Wales Hospital. The Chinese University of Hong Kong
Hong Kong, Hong Kong
Start Date
January 1, 2020
Primary Completion Date
December 31, 2026
Completion Date
June 30, 2027
Last Updated
December 9, 2025
40
ESTIMATED participants
Hydrochlorothiazide 25mg once per day
DRUG
Lead Sponsor
Chinese University of Hong Kong
NCT02417740
NCT07073820
Data Source & Attribution
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Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT07480265