Body weight greater than or equal to (≥)45 kilogram (kg)
Body mass index (BMI) ≥18 to less than (\<) 40 kilogram per meter square (kg/m\^2)
Diagnosis of diabetes mellitus type 1 or type 2 and with glycosylated hemoglobin A1c (HbA1c) ≤9% and the presence of bilateral pain in lower extremities due to DPN for at least 1 year
Weekly average of daily NPRS score ≥4 and less than or equal to (≤) 9 with limited variation in the 7-day Baseline Period
You may not be if
More than 3 missing daily NPRS scores during the 7-day Baseline Period
Received Journavx within 30 days of study drug dosing
Any sensory abnormality (excluding DPN) as pre-specified in the protocol
Clareo Health | Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy