A Phase 1, Randomized, Double-blind, Placebo-controlled Study Evaluating AMG 691 in Healthy Participants and Participants With Mild-to-Moderate Asthma

Inclusion Criteria

• •Inclusion Part A and B
• •Participants must be capable of giving informed consent and have provided informed consent.
• •Participants must be 18 to 65 inclusive at time of signing of informed consent.
• •Participants must have a Body Mass Index between 18.0 to 30 kg/m2 and total body weight ≥ 40 kg at screening.
• •Participants must be overtly healthy as determined by the investigator based on medical evaluation and study screening procedures.
• •Female participants must be of non-childbearing potential.
• •Inclusion Part C
• •Participants must be capable of giving informed consent and have provided informed consent.
• •Participants must be 18 to 65 inclusive at time of signing of informed consent.
• •Participants must have documentation of physician diagnosed asthma for ≥ 12 months prior to screening.
• +21 more criteria