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COMPLETEDNA

The Effect of Aerobic Exercise on an Elliptical Trainer Versus a Treadmill, in People With Multiple Sclerosis

The Effect of Aerobic Exercise on an Elliptical Trainer Versus a Treadmill, on Gait and Walking Abilities, Expressed in Dynamic Stability, Balance and Walking Speed, in People With Multiple Sclerosis (MS)

NCT06583967•Soroka University Medical Center

View on ClinicalTrials.gov

Summary

The aim of this study is to examine the effects of aerobic exercise training using an elliptical trainer compared to a treadmill on gait and walking abilities, expressed in dynamic stability, balance, and walking speed, in people with Multiple Sclerosis with moderate severity.

Detailed Description

A total of 30 MS subjects to be enrolled in the study. Subjects to be assigned into one of two groups named: Group 1 - Elliptical Training and Group 2 - Treadmill Training. Effort capacity will measured by heart rate and RPE. Outcome measures will be measured by using, 6 min. walking test (6MWT), Timed Up \& Go (TUG), Berg Balance Scale (BBS) and 10 Meter Walk Test (10MWT) to be used to assess the quality of life at Baseline (T0), During study - 6 weeks from baseline (T1), End of training program - 12 weeks from baseline (T2) and 6 weeks post T2 (T3). The exercise program to be applied for 12 weeks with 2 trainings per week.

Eligibility

Age

25 - 55 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. Patients signed Informed Consent Form
•2. At least 6 months post MS diagnosis
•3. 25-55 years old adults
•4. EDSS 3.0-6.5
•5. Standing stability - for at least 30 seconds
•6. 6MWT - minimal distance to be measured as 210 meters
•7. No physical routinely training e.g. walking, elliptical or cycling within 3 months prior screening visit.

Exclusion Criteria

•1. Active Heart Disease
•2. Lungs and/or respiratory system diseases
•3. Metabolic Disease
•4. Any other medical condition(s) which might impact the patient's participant in the study, as per PI medical judgement
•5. Major medical treatment change (as per PI medical judgement) up to 12 weeks prior ICF signature by the patient.

Locations (2)

Soroka Medical Center

Beersheba, Israel, Israel

Israel ParaSport Center

Ramat Gan, Israel, Israel

Key Dates

Start Date

June 1, 2024

Primary Completion Date

February 28, 2025

Completion Date

June 30, 2025

Last Updated

January 7, 2026

Enrollment

ACTUAL participants

Conditions

Multiple Sclerosis (MS)

Interventions

Physical Training

OTHER

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RECRUITINGNA

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 7, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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The Effect of Aerobic Exercise on an Elliptical Trainer Versus a Treadmill, in People With Multiple Sclerosis

Inclusion Criteria

Exclusion Criteria

Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy

Wearable Focal Vibration Therapy on Upper Extremity Function of People With Multiple Sclerosis: A Pilot Study

Pregnancy Cohort in Multiple Sclerosis (MS)

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