Male or female patients aged between 45-75 years old.
Clinical diagnosis of PD according to UK Brain Bank Criteria.
3 months of clinical stability before study enrolment.
Anti-parkinsonian medication is fixed for at least 3 months prior to study entry.
Male or female patients 18 years old or older.
Diagnosis of RR-MS according to McDonald criteria.
Expanded Disability Status Scale(EDSS) lower or equal to 5.5.
Stable disease for at least 30 days prior to study entry.
Stable disease-modifying therapy for at least 3 months prior to study entry.
No changes in drug treatment during 6 months-study treatment.
Patients understand and comply with the study procedure and are able to complete tests and examinations required by the project.
Written informed consent.
Eligible patients are those clinically stable;
Age range from 1 to 10, between 5 and 30 kg.
Patients not involved in other clinical trials.
You may not be if
Absolute contraindications to Magnetic Resonance Imaging (MRI).
Concomitant neurological disease or severe co-morbidities able to influence outcomes such as spinal injury, cancer, dementia, or other central nervous system diseases such as stroke, epilepsy or psychiatric disorders;
Total score of Mini-Mental State Examination (MMSE)\<24.
