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Wearable Focal Vibration Therapy on Upper Extremity Function of People With Multiple Sclerosis: A Pilot Study | Clinical Trials | Clareo Health

RECRUITINGNA

Wearable Focal Vibration Therapy on Upper Extremity Function of People With Multiple Sclerosis: A Pilot Study

Feasibility, Preliminary Efficacy, and User Perspective Usability of Wearable Focal Vibration Therapy on Upper Extremity Function of People With Multiple Sclerosis: A Pilot Study

NCT07376772•University of Florida

View on ClinicalTrials.gov

Summary

This pilot mixed-method study will evaluate the feasibility, preliminary efficacy, and user experience of a home-based wearable Focal Vibration Therapy (FVT) intervention for improving upper extremity (UEx) function in people with multiple sclerosis (MS). Fifteen adults with relapsing-remitting MS (PRMS) and self-reported UEx impairments will participate in a 4-week FVT program using MyovoltTM wearable FVT devices applied to arm muscles.

Eligibility

Age

18 - 100 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Aged over 18 years
•Confirmed diagnosis of RRMS according to the McDonald criteria (33)
•No MS relapse or exacerbation within the past 6 months (ensuring stability of symptoms)
•Self-report on clinical evidence of UEx impairment (including reduced arm/hand function, muscle weakness, spasticity, or pain).
•Stable on MS treatment for at least four weeks before recruitment, with no plans to initiate new treatments (participants may continue current treatments during the study)
•Agree and are able to use the FVT device after training.
•Sufficient proficiency in English to participate in interviews and follow instructions
•Able to visit the laboratory for assessments
•Able to provide written informed consent

Exclusion Criteria

•Evidence of cognitive impairment that could interfere with following instructions (Mini-Montreal Cognitive Assessment score (Mini-MoCA) \< 12)
•Comorbid neurological or psychiatric conditions affecting the UEx (including stroke and severe carpal tunnel syndrome) that would confound results or make FVT unsafe
•Unstable cardiac disease or any major medical illness that would preclude participation
•Any known contraindications to vibration therapy (pregnancy, acute deep vein thrombosis, severe osteoporosis, chronic migraines, epilepsy, active malignancy in the target area, unstable cardiac disease, or an implanted pacemaker without clearance)

Locations (2)

Norman Fixel Institute for Neurological Diseases

Gainesville, Florida, United States

University of Florida

Gainesville, Florida, United States

Key Dates

Start Date

March 4, 2026

Primary Completion Date

June 30, 2026

Completion Date

June 30, 2026

Last Updated

March 6, 2026

Enrollment

ESTIMATED participants

Conditions

Multiple Sclerosis (MS) - Relapsing-remittingUpper Extremity Dysfunction

Interventions

wearable focal vibration therapy

DEVICE

Contacts

Hongwu Wang, PhD

CONTACT

352-273-9934 hongwu.wang@ufl.edu

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ACTIVE_NOT_RECRUITINGNA

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 6, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Wearable Focal Vibration Therapy on Upper Extremity Function of People With Multiple Sclerosis: A Pilot Study

Inclusion Criteria

Exclusion Criteria

Educational Programs Based on Healthy Habits to Improve Quality of Life and Psychosocial Profile in Women With Neurodegenerative Diseases: The ADVICE Protocol Study (Phase 1)

Educational Programs Based on Healthy Habits to Improve Quality of Life and Psychosocial Profile in Women With Neurodegenerative Diseases: the ADVICE Protocol Study (Phase 2)

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