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Once Versus Twice Bisoprolol Dosage Regimen in Prevention of Atrial Fibrillation Post Coronary Artery Bypass Graft Surgery | Clinical Trials | Clareo Health

UNKNOWNPHASE4

Once Versus Twice Bisoprolol Dosage Regimen in Prevention of Atrial Fibrillation Post Coronary Artery Bypass Graft Surgery

NCT05730413•Cairo University

View on ClinicalTrials.gov

Summary

The goal of this interventional clinical trial is compare between two different dose regimens of bisoprolol (beta-blocker) in CABG patients in terms of efficacy and safety.

Eligibility

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Adult patients: 18 to 65 years old
•Diagnosed with coronary heart disease or myocardial infarction and scheduled for coronary artery bypass surgery

Exclusion Criteria

•History of Ventricular arrhythmia, atrial fibrillation, atrial flutter, left bundle block, AV block grade II/III
•History of Sick sinus syndrome, sinoatrial heart block
•History of valve replacement
•Permanent Pacemaker
•LVEF less than 30%
•Unstable Heart failure
•Cardiogenic shock
•Sustained systolic blood pressure less than 100 mmHg or HR less than 50 bpm at recruitment
•Severe chronic obstructive airway disease
•Severe asthma unless was on previously tolerated bisoprolol dose
+13 more criteria

Locations (1)

El-Demerdash Cardiac Academy Hospital

Cairo, Egypt

Key Dates

Start Date

August 25, 2021

Primary Completion Date

September 1, 2023

Completion Date

September 1, 2023

Last Updated

July 28, 2023

Enrollment

122

ESTIMATED participants

Conditions

Coronary Artery Bypass GraftingPostoperative Atrial FibrillationCoronary Artery Disease

Interventions

Bisoprolol

DRUG

Bisoprolol

DRUG

Contacts

Reem Ihab, Bsc

CONTACT

+0201144481391 reem.ihab@pharma.cu.edu.eg

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 28, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Once Versus Twice Bisoprolol Dosage Regimen in Prevention of Atrial Fibrillation Post Coronary Artery Bypass Graft Surgery

Inclusion Criteria

Exclusion Criteria

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