Coronary Artery Stents in Heart Failure With Preserved Ejection Fraction

Inclusion Criteria

• •1\. A diagnosis of HFpEF, defined by the European Society of Cardiology (ESC) criteria, defined as:
• •1. Symptoms of heart failure (New York Heart Association (NYHA) class II-IV) and
• •2. Left ventricular ejection fraction ≥ 50% and
• •3. NT-pro-BNP \> 125 pg/ml in sinus rhythm or \> 365 pg/ml in atrial fibrillation and
• •4. One or more of the following objective signs of left ventricular diastolic dysfunction:
• •i. Invasively measured left ventricular end diastolic pressure ≥ 15 mmHg at rest or ≥ 25 mmHg on exercise (directly measured or estimated via pulmonary capillary wedge pressure) ii. Estimated pulmonary artery systolic pressure \> 35mmHg or tricuspid regurgitation velocity \> 2.8 m/s on echocardiography iii. Left atrial volume index \> 34ml/m2 in patient in sinus rhythm or left atrial volume index \> 40ml/m2 in atrial fibrillation iv. Relative left ventricular wall thickness \> 0.42 v. Left ventricular mass index ≥ 95 g/m2 in females or ≥ 115 g/m2 in males vi. Mitral E/E' ratio \> 9