Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of North Carolina, Chapel Hill
Age
50–90
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Men and women between 50 and 90 years of age, without a diagnosis of severe dementia
Carry a diagnosis of idiopathic Parkinson's disease based on the United Kingdom Parkinson's Disease Society Brain Bank clinical diagnostic criteria
Have had symptoms of Parkinson's disease for at least 3 years
Hospital's study-specific informed consent must be obtained
Must have capacity to provide informed consent in English
For female participants, confirmation that a menstrual period has not occurred in over 12 months, or that an effective form of contraception will be used during the study
You may not be if
Inability to provide informed consent.
Severe dementia
History of epilepsy or brain surgery
Severe tremor or dyskinesia that would interfere with EEG as determined by the PI
Parkinson's patients with clinically significant medical or neurological conditions which may be an alternative cause of orthostatic hypotension, such as neuropathy, renal failure, heart failure, cardiac arrhythmias, severe diabetes, or spinal cord injuries
The investigators will exclude patients who are treated with medications which can significantly lower blood pressure or heart rate, such as antihypertensive medications, diuretics, and alpha-blocking medications
Presence of other known central nervous system disease that may interfere with performance or interpretation of EEG or TMS
Presence of any implanted metal devices including, but not limited to, pacemakers, deep brain stimulators, vagal nerve stimulators, bladder stimulators, or cochlear implants.
