Clinical Outcome and Cost-effectiveness of Reduced Noradrenaline by Using a Lower Blood Pressure Target in Patients With Cardiogenic Shock From Acute Myocardial Infarction

Inclusion Criteria

• •1. Acute myocardial infarction, STEMI or NSTEMI
• •2. Early revascularization by PCI
• •3. Cardiogenic shock, characterized by:
• •I. a. Systolic blood pressure (SBP) ≤ 90 mmHg for \> 30 minutes, OR b. Use of drugs to maintain SBP \> 90 mmHg at randomization.
• •II. Clinical signs of impaired organ perfusion with at least one of the following criteria:
• •1. Altered mental status
• •2. Cold, clammy skin and extremities
• •3. Oliguria with urine output \< 30ml/hour
• •4. Serum lactate \> 2.0 mmol/L
• •III. Clinical signs of pulmonary congestion