Complete Functional Assessment of Intermediate Coronary Artery Stenosis Before and After Transcatheter Aortic Valve Implantation (TAVI) in Patients With Severe Symptomatic Aortic Valve Stenosis

Inclusion Criteria

• •Age \>18 years
• •Willing to participate and able to understand, read and sign the informed consent document before the planned procedure
• •Severe symptomatic aortic stenosis with indication for TAVI according to current guidelines deemed by the Heart Team
• •Patients who have undergone coronary CT angiography before TAVI in which CAD could not be ruled out
• •CAD in one or more native major epicardial vessels or their branches by coronary angiogram with visually assessed coronary stenosis, in which the physiological severity of the lesion is in question (typically 40-90% diameter stenosis).
• •Eligible for invasive coronary angiography and functional assessment (FFR, RFR, CFR and IMR)
• •Eligible for coronary CT-angiography and functional assessment (CT-FFR)