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Pre-procedural Assessment of Coronary Artery Disease in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI) - Comparision of Pre-TAVI CTA vs. Pre-TAVI ICA
ICA is not always required for a pre-TAVI workup of octogenarians and can be substituted by CTA resulting in a streamlined pre-procedural workup of patients without compromising patient safety.
Patients undergoing TAVI require routine pre-procedural assessment of CAD (coronary artery disease). ICA (invasive coronary angiography) is the gold standard in patients with high pre-test probability. It is associated, however, with procedural risk, radiation and cost. CTA (computed tomography angiography) currently has limited use for the evaluation of CAD in pts with severe symptomatic AS (aortic stenosis) - medications required such as beta blockers and nitroglycerine, are frequently not well tolerated by pts. But as TAVI is increasingly being performed in patients with modest pre-test probabilities for obstructive CAD or a lack of implications thereof (pts. ≥75 yrs), the use of CTA may become more appealing.
Age
75 - No limit years
Sex
ALL
Healthy Volunteers
No
Universitätsklinik für Innere Medizin III - Kardiologie und Angiologie
Innsbruck, Tyrol, Austria
University Clinic St. Pölten
Sankt Pölten, Austria
Medical University of Vienna
Vienna, Austria
Klinik Floridsdorf
Vienna, Austria
University Hospital Bochum / HDZ NRW
Bad Oeynhausen, North Rhine-Westphalia, Germany
University Hospital of the Bergmannsheil gGmbH
Bochum, North Rhine-Westphalia, Germany
Start Date
September 1, 2023
Primary Completion Date
August 1, 2025
Completion Date
August 1, 2025
Last Updated
June 15, 2025
150
ESTIMATED participants
Streamlining of the pre-procedural patient pathway
OTHER
Lead Sponsor
Institut für Pharmakologie und Präventive Medizin
Collaborators
Data Source & Attribution
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