Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Hvidovre University Hospital
With
Innovation Fund Denmark
Naestved Hospital
The purpose of this study is to examine if automated oxygen control based on pulse oximetry to patients with domiciliary long-term oxygen treatment (LTOT) is better than manually controlled oxygen treatment in keeping SpO2 within intended target interval. In manually controlled oxygen treatment flow is usually kept constant for months between visits from specialist nurse, whereas in automated control the patient can titrate oxygen flow several times a day based on pulse oximetry in a closed-loop system.
Age
40–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Verified COPD with FEV1/FVC \< 0.70
Need of LTOT (PaO2 \<= 7.3 kPa or SpO2 \< 88 % on ambient air)
Cognitively able to participate
Willing to provide informed consent
You may not be if
Moderate or severe exacerbation in COPD within 4 weeks from study start
Major comorbidities (cancer, uncontrolled chronic disease)
Asthma or other disease with need of higher SpO2
Pregnancy
Fall in pH below 7.35 or increase in PaCO2 \> 1 kPa on 5 liters of oxygen
Active smoking
LTOT use less than 1 hours/day
Clareo Health | Automated Oxygen Titration with O2matic Home Oxygen Therapy (O2matic HOT) Phase 1
