Lead Sponsor

Yale University

Collaborators

Age

18 - 72 years

Sex

ALL

Healthy Volunteers

No

•adults 18+
•able to read and understand English at 5th grade level
•permanently reside in the United States
•have pain interference aggregate scores of three or more in the last two weeks using the Brief Pain Inventory-Short Form (BPI-SF) scale

•have an undiagnosed case of NF1
•have documented major co-occurring psychiatric disease
•have moderate to severe cognitive deficits
•have depression assessed using the Patient Health Questionnaire (PHQ-9) or anxiety assessed using the Generalized Anxiety Disorder scale (GAD-7) greater than or equal to the appropriate thresholds (10=mild major depression; 5=mild severe anxiety)