Analgesic Efficacy of Multisite rTMS in Fibromyalgia Patients

Exclusion Criteria

• •Ongoing litigation;
• •Contraindication to rTMS:
• •Implanted electronic devices and/or conductive objects near the coil: Patients with an active implanted device that is activated or controlled by physiological signals (e.g., pacemakers, implantable cardiac defibrillators \[ICD\], vagus nerve stimulators \[VNS\], wearable cardioverter defibrillators \[WCD\], ocular implants, deep brain stimulation systems, drug infusion pumps or ports, intracardiac leads), even if the device has been removed.
• •Non-removable metallic objects near the coil:\*\* Patients with a conductive, ferromagnetic, or magnetically sensitive metal implant in the head or within 30 cm of the coil (e.g., cochlear implants, implanted electrodes/stimulators, aneurysm clips or coils, stents, or bullet fragments);
• •Current abuse of drugs or psychoactive substances, including alcohol (according to DSM-5 criteria);
• •Pregnancy or breastfeeding;
• •Epilepsy or a history of epilepsy;
• •Unstable or progressive medical conditions (e.g., cancer);
• •Psychosis according to DSM-5 criteria;
• •Presence of another pain condition more severe than the one qualifying for inclusion;
• •Failure to correctly complete pain self-assessment diaries between inclusion and randomization (fewer than 4 pain scores recorded over 7 days);
• •Inability to understand the informed consent form, or subjects under legal guardianship or curatorship;
• •Participation in another research protocol within 30 days prior to inclusion.