Ascending Glycan Dietary Supplementation in Healthy Adults

Exclusion Criteria

• •Women who are pregnant, actively nursing, or pregnant within the last year
• •Women who are peri-menopausal or post-menopausal
• •Women with irregular menstrual cycles (more frequently than every 21 days or lasts longer than 8 days (missed, early, or late periods are also considered signs of an irregular cycle).
• •Women on hormonal contraception, including birth control, hormonal intrauterine device, or contraceptive implant
• •Past medical history of an autoimmune condition or malignancy, excluding non-melanoma skin cancer
• •Individuals with first degree relative with history of an autoimmune condition
• •Individuals with cardiovascular, pulmonary, reproductive, endocrine, metabolic, neurologic, gastrointestinal, hematologic, or infectious diseases of any kind
• •Individuals with diagnosis of galactosemia or congenital disorders of glycosylation
• •Individuals with phenylketonuria
• •Individuals currently taking prescription medications, or have taken prescription medications within the last 3 months
• •Individuals currently taking over the counter medications
• •Individuals currently taking or have taken supplements including herbal, protein or vitamin supplements in the last 3 months (e.g. whey protein, St. John's Wort, green tea supplements, biotin, creatine supplements), excluding multivitamins or essential vitamins
• •Individuals with prior history of severe food or drug allergic reactions
• •Individuals with a diagnosis of type I or II diabetes mellitus
• •Individuals with allergic reaction or adverse reaction to shellfish, N-acetyl glucosamine, galactose, or Spirulina/chlorella/algae supplements
• •Individuals with social history of current use of tobacco, alcohol or other drugs
• •* Actively dieting or trying to lose weight
• •* Vegan diet
• •* Consume equal to or greater than 2 cups of tea a day
• •* Consume equal to or greater than 4 cups of coffee a day
• •* Consume equal to or greater than 3 cups of fruit juice a day
• •* Practice intensive exercise patterns (marathon training, workouts \>4 hours a day)
• •* Consume soda or energy drinks of any amount
• •* On a carbohydrate-restricted or "Paleo" diet
• •* Calorie-restricted diet (less than 20%-25% of maintenance calories)