Masitinib in the Treatment of Patients With Severe Uncontrolled Asthma and Elevated Eosinophil Levels

Exclusion Criteria

• •Female patient who is pregnant or lactating
• •Asthmatic patient still exposed to allergens or to triggering factors influencing asthma control
• •Chronic obstructive pulmonary disease and/or other lung diseases impairing Pulmonary Function Tests
• •Within 12 weeks prior to screening, patient who received oral corticosteroids for any other reason than to treat severe asthma exacerbation (patients needing long term corticosteroids intake to control basal asthma condition)
• •Patient with history of acute infectious sinusitis or respiratory tract infection within 4 weeks prior to screening visit
• •Patient with active lung disease other than asthma (e.g. chronic bronchitis)