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Palliative Thoracic ImmunoRT | Clinical Trials | Clareo Health

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Active Not RecruitingNCT03705806

Palliative Thoracic ImmunoRT

The trial is designed as a prospective observational single arm study investigating stage IV non-small cell lung cancer patients who are routinely treated with a PD-1 inhibitor for indications approve...

Lead sponsor: University Health Network, Toronto•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

University Health Network, Toronto

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Exclusion Criteria

•2. Indication and suitability to receive palliative radiotherapy to the thorax (30Gy/10).
•3. Receiving or planned to receive nivolumab or pembrolizumab
•4. Prior history of systemic chemotherapy is permitted given a washout period of 4 weeks
•5. Age 18 or older
•6. ECOG Performance Status 0-2
•7. Life expectancy greater than 3 months
•8. Able and willing to provide informed consent
•9. Able to complete patient reported outcome questionnaires
•1. Contraindications to radiotherapy, including a history of SLE, systemic scleroderma, IPF, ataxia telangiectasia
•2. Previous history of thoracic radiotherapy with an overlapping field
•3. Previous history of checkpoint inhibitor related pneumonitis or esophagitis
•4. Pregnancy

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: March 4, 2026Terms

Trial snapshot

StatusACTIVE_NOT_RECRUITING

Phase—

Enrollment12

Start dateOct 2018

Last updatedMar 4, 2026

Condition

Lung Cancer, Nonsmall Cell Lung Cancer

Locations shown

University Health Network, Princess Margaret Cancer Centre

Toronto, Ontario

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 4, 2026Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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