Lead Sponsor

Johns Hopkins University

Age

18 - 95 years

Sex

ALL

Healthy Volunteers

No

•Pre-catheterization
•1. must be undergoing diagnostic cardiac catheterization for suspected CAD
•2. be at least 18 years of age
•3. must not be pregnant (negative pregnancy test) or must not be of childbearing potential
•4. must be able to give informed consent. Post-catheterization
•5. coronary artery disease judged to be clinically and angiographically significant
•6. ability to perform PCI with equipment available at the local site (see below)
•7. procedure risk judged to be not high (see below)

•Pre-catheterization
•1. inability to give informed consent
•2. ST-segment elevation myocardial infarction
•3. pregnancy Post-catheterization
•4. high likelihood of requiring a device not available at the hospitals without SOS (see below)
•5. no need for PCI
•6. need for coronary artery bypass surgery
•7. high procedural risk (see below)