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Hippocampus Avoidance PCI vs PCI | Clinical Trials | Clareo Health

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COMPLETEDPhase 3NCT01780675

Hippocampus Avoidance PCI vs PCI

Using Intensity Modulated radiotherapy it is possible to treat the entire brain to standard dosages of whole-brain radiation, while keeping the radiation dose to the hippocampus low. However, a clear ...

Lead sponsor: The Netherlands Cancer Institute•9 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

The Netherlands Cancer Institute

Collaborators

Dutch Cancer Society

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•\- Small Cell Lung Cancer patients (stage I-III or stage IV without clinical or radiological evidence of brain metastases) candidate for PCI, i.e. without progressive disease after chemo-radiotherapy in stage I-III or after a remission after chemotherapy in stage IV
•Sufficient proficiency in Dutch

Exclusion Criteria

•Prior radiotherapy to the brain
•Clinical evidence for brain metastases or primary brain tumors- Evidence of progressive extracranial metastatic disease
•Previous malignancy \< 2 years ago except for adequately treated basal cell carcinoma of the skin and carcinoma in situ of the cervix
•Any systemic anticancer treatment during PCI or within 3 weeks before start PCI
•Pregnancy or lactation

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: January 21, 2022Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE3

Enrollment168

Start dateApr 2013

Last updatedJan 21, 2022

Condition

Small Cell Lung Cancer Lung Cancer

Locations shown

Universitair Ziekenhuis Antwerpen

Antwerp

Universitair Ziekenhuis Gent

Ghent

Universitair Ziekenhuis Leuven

Leuven

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 21, 2022Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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