Angiotensin II Blockade and Inflammation in Obesity

Exclusion Criteria

• •Blood pressure outside stated range
• •Diabetes or taking diabetes medications
• •Total cholesterol \>6.2 mmol/L; triglycerides \>4.5 mmol/L
• •Past or current ischemic heart disease, stroke, respiratory disease, endocrine or metabolic disease, neurological disease, or hematological-oncological disease
• •Evidence of renal insufficiency; GFR\< 60 ml/min\*
• •Medications (including but not limited to antihypertensives, statins or other with anti-inflammatory actions) or antioxidant vitamins or supplements
• •Known allergy or hypersensitivity to olmesartan or any of its components
• •Pregnant or planning to become pregnant