Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Merck Sharp & Dohme LLC
Age
18–40
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Must be in good health
Must have a body mass index greater than or equal to 18 kg/m\^2 and less than or equal to 30 kg/m\^2
You may not be if
Is pregnant, nursing, or plans to become pregnant
Has clinically significant cardiovascular, renal, hepatic, gastrointestinal (GI), neurological, endocrine, hematological, dermatological or metabolic disease, or clinically significant abnormalities, as determined by medical history, physical examination, electrocardiogram, vital signs, or laboratory tests
Has a history of migraine headaches
Has a history of recent lumbar CSF sampling within 3 weeks prior to screening, history of lumbar spine surgery, or chronic low back pain or injury
Has an infection or inflammation of the skin in or in close proximity to the area of the lumbar puncture site
Has a history of a seizure disorder
Is noted to have papilledema or clinically significant focal neurological deficits at the screening physical examination, as well as abnormalities of CSF pressure on initial testing once access to the lumbar space is achieved
Has absolute or relative anatomic abnormalities that would be a contraindication to lumbar puncture
Is a heavy consumer of alcohol
Has used nicotine in the past 6 months
Has a history of a significant psychiatric disorder
