Study of Asthma and Nasal Steroids

Exclusion Criteria

• •Co-morbidity that predisposes to complicated rhino-sinusitis (e.g., cystic fibrosis, insulin dependent diabetes mellitus, immunodeficiency disorder)
• •Chronic diseases (other than asthma) that in the opinion of the investigator would prevent participation in the trial or put the participant at risk by participation, e.g. chronic diseases of the lung (other than asthma), heart, liver, kidney or nervous system.
• •History of sinus surgery in last 6 months
• •Systemic/nasal steroids within last 4 weeks
• •Anti-leukotriene medication
• •History of upper airway symptoms for less than 8 weeks at the time of enrollment
• •Fever \> 38.3 degrees Celsius or patient history of fever in last 10 days
• •Greater than 10 pack year smoking history or active smoking within the last 6 months
• •FEV1 \< 50% predicted
• •Females of childbearing potential that are pregnant or lactating, or unwilling to practice an adequate birth control method
• •Allergy or intolerance to nasal mometasone
• •Cataracts, history of glaucoma, or other conditions resulting in increased intraocular pressure
• •Any investigational drug in the last 6 weeks
• •Inability to comply with study procedures, including:
• •* Inability or unwillingness to provide informed consent (or assent in the case of a minor)
• •* Inability to take study medication
• •* Inability to perform baseline measurements
• •* Completion of less than 10 of the 14 days of screening period diary entry
• •* Inability to be contacted by phone
• •* Intention to move out of the area within 6 months