A Study of Acupuncture for Patients With Behavioural and Psychological Symptoms of Dementia

Exclusion Criteria

• •1. Received a diagnosis of a primary psychotic disorder (e.g.schizophrenia，bipolar disorder, severe or recurrent depression),other dementia such as vascular dementia,complex dementia or Lewy-body dementia,or psychosis,agitation, or aggression that could be better accounted for by another medical condition, or substance abuse
• •2. Had severe system disease (e.g., cardiovascular, hepatorenal, hematopoietic system) or infectious disease
• •3. Received medication (e.g.,benzodiazepines, antipsychotics, or anticholinergics)which could treat BPSD within 2 weeks prior to the first acupuncture of the study
• •4. Participated in any clinical trial of drug within 4 weeks prior to the study
• •5. History of taking acupuncture
• •The eligibility criteria of the healthy volunteers arm:
• •1. History of significant neurological (including history of seizures,EEG abnormalities or dementia) or psychotic disorder (e.g.schizophrenia，bipolar disorder, severe or recurrent depression)
• •2. History of drug or alcohol abuse
• •3. History of taking medication that may be impair the function of cognition or psychotic behavior within 4 weeks before the study
• •4. Participated in any clinical trial of drug within 4 weeks prior to the study
• •5. History of taking acupuncture