A Study To Investigate Whether PF-04457845 Is Effective In Treating Pain, Is Safe And Tolerable In Patients With Osteoarthritis Of The Knee

Inclusion Criteria

• •Subjects must have a diagnosis of Osteoarthritis (OA) of the knee confirmed by X-ray
• •Subjects must be willing and able to stop all current pain therapy for the duration of study. (Limited and specific pain therapy will be available throughout the study)
• •Subjects can be male or female between the ages of 18 and 75 years inclusive, but female subjects must not be able become pregnant