Efficacy of Chemoradiotherapy After Neoadjuvant Cisplatin and Docetaxel in the Nasopharynx Carcinoma

Exclusion Criteria

• •Patients with stage IVC or metastatic disease
• •Patients treated with chemotherapy for nasopharyngeal cancer
• •Patients treated with radiotherapy to head and neck region
• •Concomitant use of another anti-cancer therapy
• •Patients treated with amifostine or pilocarpine during protocol treatment.
• •Unstable medical condition that makes the patient unable to take part in a clinical study (congestive heart failure, serious arrhythmia, uncontrolled diabetes mellitus), history of myocardial infarction within last 6 months, massive pleural, peritoneal or pericardial effusion; or presence of serious uncontrolled infection.
• •Presence of other tumours different from carcinoma of the skin except melanoma and carcinoma in situ of the breast and cervix with disease free survival less than 5 years.
• •Pregnancy or breastfeeding. In women of childbearing potential and in men, an adequate contraceptive method must be used
• •Social or psychological condition that render the patient inadequate for the follow-up of the study
• •Contraindication for any of the study drugs (e.g. history of hypersensitivity to any of the ingredients of the study drugs)
• •The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.