Neurostimulation for the Relief of Acute Bronchoconstriction

Exclusion Criteria

• •Scaring / abscess other problems with neck at electrode placement site
• •Known or suspected carotid artery disease (i.e. bruits or history of stenosis)
• •Suspected or confirmed coagulopathy
• •Suspected or confirmed sepsis
• •Irregular heart rate, rhythm
• •Receiving pressors to maintain blood pressure
• •Presently implanted electrical and/or neurostimulator device, including but not limited to cardiac pacemaker, vagal neurostimulator, deep brain stimulator, spinal stimulator, bone growth stimulator, or cochlear implant
• •Allergy to local anesthetics used for placement of the lead
• •History of lung cancer, emphysema, chronic obstructive pulmonary disease, or other comorbidity that might otherwise compromise the expected air flow volumes in the lungs
• •At risk of imminent respiratory collapse
• •* Lung Function: FEV1 \< 40% predicted
• •* Signs and Symptoms: Extreme symptoms at rest, accessory muscle use, chest retraction
• •* Alert State: Drowsy, confused
• •Treatment with anti-cholinergic medications within 4 hours of enrollment