Medicinal Cannabis for Painful HIV Neuropathy

Exclusion Criteria

• •Positive urine toxicology screen for cannabinoids during the "wash-in" week prior to initiating study treatment
• •Recent (i.e. during the month prior to study entry) history of marijuana use more than twice a week
• •Previous psychosis with or intolerance to cannabinoids
• •A lifetime history (ever) of dependence on cannabis
• •Meeting criteria for alcohol or drug dependence within the last 12 months
• •Active, major psychiatric disorder likely, in the investigator's opinion, to interfere with adherence to the study protocol
• •Active AIDS-defining opportunistic disease (a history of AIDS-defining opportunistic disease which is no longer active or progressing will not be grounds for exclusion)
• •Diabetes mellitus, renal failure with uremia, alcohol abuse, previous spinal surgery, or other documented causes of neuropathy or neuropathic pain
• •Pulmonary disease of sufficient severity to require the use of supplemental oxygen
• •Asthma
• •Life expectancy less than 6 weeks or an active, acute illness likely to interfere with completion of the study protocol
• •Pregnancy
• •Failure to use adequate birth control in an individual with reproductive potential
• •Minority status (less than 21 years), or persons over age 65 years